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European Training Network on Cancer-Induced Bone Diseases

European Training Network on Cancer-Induced Bone Diseases

Objective

Several cancers are prone to metastasize to bone. Combating bone metastasis, especially the early dissemination of cancer cells in bone, requires basic research knowledge, skills in different technologies and longstanding clinical experience in order to make clinically significant progress. BONE-NET is a european consortium with complementary expertises in the fields of cancer and bone. It brings together 6 leading academic groups and 3 SMEs. BONE-NET’s scientific project will aim at investigating the early molecular mechanisms of metastases associated with breast and prostate cancers and primary bone cancers (e.g., osteosarcomas), including the identification of new genes and their regulators (microRNAs) that draw cancer cells to colonize bone and let these cells adapt and thrive in the bone marrow. This network will then seek to identify and develop molecularly-targeted therapies. BONE-NET’s primary objective will be to train 11 early-stage (ESR) and 3 experienced (ER) researchers in technical skills such as genomics, proteomics, advanced microscopical methods, animal experimentation, noninvasive in vivo imaging methodologies and drug development. None of the participating laboratories use all of these approaches, but through workshops, courses and secondments ESR/ER will become expert in many of these disciplines. The network additional objective will be to foster collaborations between participating laboratories, in which ESR/ER will take part through individual training-through-research projects. The training programme will also expose the ESR/ER to the industry which will offer courses and a set of complementary skills (ethics, intellectual property rights, entrepreneurship), thereby enabling them to gain industrial work experience. Overall, at the end of the project, ESR/ER will have acquired enough skills in order to manage their own research programmes and to envisage attractive career perspectives within Europe.

Coordinator

UNIVERSITE LYON 1 CLAUDE BERNARD

Address

Boulevard Du 11 Novembre 1918 Num43
69622 Villeurbanne Cedex

France

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 781 118,90

Administrative Contact

Javier Olaiz (Dr.)

Participants (10)

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THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN

United Kingdom

ITA-SUOMEN YLIOPISTO

Finland

EU Contribution

€ 520 682,80

ACADEMISCH ZIEKENHUIS LEIDEN

Netherlands

EU Contribution

€ 453 246,30

UNIVERSITE DE LIEGE

Belgium

EU Contribution

€ 233 870

UNIVERSITE DE NANTES

France

EU Contribution

€ 462 009,40

DNA VISION SA

Belgium

MED DISCOVERY SA

Switzerland

UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF

Germany

EU Contribution

€ 377 358

THE UNIVERSITY OF SHEFFIELD

United Kingdom

EU Contribution

€ 217 055

GENOMIC INVESTMENTS BV

Netherlands

EU Contribution

€ 218 524

Project information

Grant agreement ID: 264817

Status

Closed project

  • Start date

    1 February 2011

  • End date

    31 January 2015

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 3 263 864,40

  • EU contribution

    € 3 263 864,40

Coordinated by:

UNIVERSITE LYON 1 CLAUDE BERNARD

France