Objective Synthesis is a fundamental area of science that is crucial to advances in medicine and materials - fields that directly impact modern society. The increasing challenges that our society presents has raised the demands on synthesis to provide new molecules that can perturb biological function or provide a new physical property. This fellowship aims to provide solutions to these problems by developing pioneering synthesis blueprints for how chemists can make any molecule in an efficient, rapid and green fashion. In particular, direct benefits of this research will be realized in the treatment of disease.The bond forming processes that underline our ability to make molecules, large or small, depends on the manipulation of pre-functionalized molecules (compounds that need to be prepared through additional synthetic steps). However, the most common type of chemical bond in almost all organic molecules is the C H bond. Usually, all but a few of these C H bonds are considered as inert and only useful in synthesis if they are in the vicinity of a one of these activating functional groups. To a synthetic chemist, permitting the use of any C H bond as a potential functional group would be like giving them a key to a new world Discovery of new chemical reactivity would lead to new reactions; comprised into a new tool kit for synthetic chemists, this would provide the basis for a molecule-building blueprint that would challenge synthetic dogma. Furthermore, using the traditionally inert C H bond as a versatile functional group would save synthesis time, make synthesis greener , and hence more efficient and cost effective. Therefore, to be able to introduce a general blueprint for chemical synthesis based using any C H bond as a versatile functional group would be a truly paradigm shifting advance, and could have enormous impact on many of the scientific challenges that affect modern society. Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-SG-PE5 - ERC Starting Grant - Materials and Synthesis Call for proposal ERC-2010-StG_20091028 See other projects for this call Funding Scheme ERC-SG - ERC Starting Grant Host institution THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE EU contribution € 1 499 983,00 Address TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge United Kingdom See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Principal investigator Matthew James Gaunt (Dr.) Administrative Contact Renata Schaeffer (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Beneficiaries (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE United Kingdom EU contribution € 1 499 983,00 Address TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Principal investigator Matthew James Gaunt (Dr.) Administrative Contact Renata Schaeffer (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
