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Sponge Enzymes and Cells for Innovative AppLications

Sponge Enzymes and Cells for Innovative AppLications

Objective

The SPECIAL project aims at delivering breakthrough technologies for the biotechnological production of cellular metabolites and extracellular biomaterials from marine sponges. These include a platform technology to produce secondary metabolites from a wide range of sponge species, a novel in vitro method for the production of biosilica and recombinant technology for the production of marine collagen.
Research on cellular metabolites will be based upon our recent finding that non-growing sponges continuously release large amounts of cellular material. Production of biosilica will be realized through biosintering, a novel enzymatic process that was recently discovered in siliceous sponges. Research on sponge collagen will focus on finding the optimal conditions for expression of the related genes.
Alongside this research, the project will identify and develop new products from sponges, thus fully realizing the promises of marine biotechnology. Specifically, the project will focus on potential anticancer drugs and novel biomedical/industrial applications of biosilica and collagen, hereby taking advantage of the unique physico-chemical properties of these extracellular sponge products.
The consortium unites seven world-class research institutions covering a wide range of marine biotechnology-related disciplines and four knowledge-intensive SMEs that are active in the field of sponge culture, drug development and nanobiotechnology.
The project is clearly reflecting the strategic objectives outlined in the position paper European Marine Strategy (2008); it will enhance marine biotechnology at a multi-disciplinary, European level and provide new opportunities for the European industry to exploit natural marine resources in a sustainable way. In particular the biotechnological potential of marine sponges, which has for a long time been considered as an eternal promise, will be realized through the SPECIAL project.

Coordinator

UNIVERSIDADE DO MINHO

Address

Largo Do Paco
4704 553 Braga

Portugal

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 532 932

Administrative Contact

Rui L. Reis (Prof.)

Participants (10)

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TEL AVIV UNIVERSITY

Israel

EU Contribution

€ 413 500

Porifarma BV

Netherlands

EU Contribution

€ 405 570

STUDIO ASSOCIATO GAIA SNC DEI DOTTORI ANTONIO SARA E MARTINA MILANESE

Italy

EU Contribution

€ 178 000

UNIVERSITA DEGLI STUDI DI GENOVA

Italy

EU Contribution

€ 264 000

UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ

Germany

EU Contribution

€ 466 350

National Research Center for Geoanalysis

China

EU Contribution

€ 131 320

KAROLINSKA INSTITUTET

Sweden

EU Contribution

€ 233 832

ATRAHASIS SRL

Italy

EU Contribution

€ 164 700

UNIVERSIDADE DOS ACORES

Portugal

EU Contribution

€ 100 878

NANOTECMARIN GMBH

Germany

EU Contribution

€ 100 600

Project information

Grant agreement ID: 266033

Status

Closed project

  • Start date

    1 December 2010

  • End date

    30 November 2013

Funded under:

FP7-KBBE

  • Overall budget:

    € 3 868 136

  • EU contribution

    € 2 991 682

Coordinated by:

UNIVERSIDADE DO MINHO

Portugal