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Epidemiological study to quantify risks for paediatric computerized tomography and to optimise doses.

Objective

Diagnostic radiation represents an indispensable, sometimes life-saving, tool in modern medicine. However, the growing use of computerized tomography (CT) is a topic of concern in radiological protection, especially for children and adolescents. Children are generally more sensitive to the carcinogenic effects of ionizing radiation than adults. In addition, they have a longer life-span to express any effect and, because of their smaller mass, they may receive higher radiation doses from a CT scan than an adult.
A large-scale multinational collaborative study will be set up with the objective of providing guidance towards optimisation of doses from paediatric CT scans. We have the following specific aims: 1) describe the pattern of use of CT in different countries and over time; 2) derive individual estimates of organ doses ; 3) assess biological markers of CT-irradiation effects; 4) directly evaluate radiation-related risk of cancer following CT; and 5) characterize the quality of CT images in relation to the estimated doses in order to better inform CT imaging practice.
Scientists from nine European countries with expertise in epidemiology, clinical practice, radiology, dosimetry, biology and public health will contribute to the project with the objective of provide recommendations for a “harmonized” approach to CT dose optimisation for paediatric patients in Europe. Results of this research will serve to increase awareness of the scientific and medical communities about public health aspects related to the use of diagnostic radiation and to provide recommendations on the use of valuable diagnostic tools, with lowering the risk of its potential hazards as much as possible.

Call for proposal

FP7-Fission-2010
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Coordinator

CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER
Address
150 Cours Albert Thomas
69372 Lyon Cedex 08
France

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Activity type
Research Organisations
Administrative Contact
Olaf Kelm (Dr.)
EU contribution
€ 303 945

Participants (19)

UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ
Germany
EU contribution
€ 294 800
Address
Langenbeckstrasse 1
55131 Mainz

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Uta Veith (Dr.)
SATEILYTURVAKESKUS
Finland
EU contribution
€ 40 102
Address
Jokiniemenkuja 1
01370 Vantaa

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Activity type
Research Organisations
Administrative Contact
Carita Lindholm (Dr.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 290 806
Address
Nobels Vag 5
17177 Stockholm

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Caroline Hamilton (Ms.)
UNIVERSITY OF NEWCASTLE UPON TYNE
United Kingdom
EU contribution
€ 401 539
Address
Kings Gate
NE1 7RU Newcastle Upon Tyne

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Aleona Blinova (Ms.)
FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL

Participation ended

Spain
Address
Calle Doctor Aiguader 88
08003 Barcelona

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Activity type
Research Organisations
Administrative Contact
Carol Barnwell (Ms.)
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain
EU contribution
€ 419 033
Address
C Rossello 132 Planta 05
08036 Barcelona

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Activity type
Research Organisations
Administrative Contact
Laura Argente (Ms.)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Address
Rue De Tolbiac 101
75654 Paris

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Activity type
Research Organisations
Administrative Contact
Teddy Petris (Mr.)
KRAEFTENS BEKAEMPELSE
Denmark
EU contribution
€ 168 960
Address
Strandboulevarden 49
2100 Koebenhavn

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Activity type
Research Organisations
Administrative Contact
Claus Skytte Rasmussen (Mr.)
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Netherlands
EU contribution
€ 307 588
Address
Plesmanlaan 121
1066 CX Amsterdam

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Activity type
Research Organisations
Administrative Contact
Henri Van Luenen (Dr.)
STUDIECENTRUM VOOR KERNENERGIE / CENTRE D'ETUDE DE L'ENERGIE NUCLEAIRE
Belgium
EU contribution
€ 286 121
Address
Avenue Herrmann Debroux 40
1160 Bruxelles

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Activity type
Research Organisations
Administrative Contact
Filip Vanhavere (Dr.)
INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE
France
EU contribution
€ 305 062
Address
Av De La Division Leclerc 31
92260 Fontenay Aux Roses

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Activity type
Research Organisations
Administrative Contact
Didier Mestraletti (Mr.)
CENTRE D'ASSURANCE DE QUALITE DES APPLICATIONS TECHNOLOGIQUES DANS LE DOMAINE DE LA SANTE
France
EU contribution
€ 57 379
Address
Avenue De L'europe 25
92310 Sevres

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Carlo Maccia (Mr.)
LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY
Luxembourg
EU contribution
€ 68 000
Address
5 Avenue Des Hauts Fourneaux
4362 Esch Sur Alzette

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Activity type
Research Organisations
Administrative Contact
Andreas Jahnen (Mr.)
CENTRE DE RECHERCHE PUBLIC HENRI TUDOR

Participation ended

Luxembourg
Address
Avenue J F Kennedy 29
1855 Luxembourg

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Activity type
Research Organisations
Administrative Contact
Andreas Jahnen (Mr.)
DIREKTORATET FOR STRALEVERN OG ATOMSIKKERHET
Norway
Address
Grini Naeringspark 13
1332 Osteraas

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Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Astrid Liland (Ms.)
OSLO UNIVERSITETSSYKEHUS HF
Norway
Address
Kirkeveien 166 Tarnbygget
0450 Oslo

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Geir Gogstad (Dr.)
INSTITUT CURIE
France
EU contribution
€ 8 220
Address
Rue D'ulm 26
75231 Paris

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Activity type
Research Organisations
Administrative Contact
Corinne Cumin (Ms.)
UNIVERSITEIT GENT
Belgium
EU contribution
€ 27 039
Address
Sint Pietersnieuwstraat 25
9000 Gent

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Margo Baele (Dr.)
BUNDESAMT FUER STRAHLENSCHUTZ
Germany
EU contribution
€ 20 000
Address
Willy-brandt-strasse 5
38226 Salzgitter

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Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Susan Fischer (Ms.)