CORDIS
EU research results

CORDIS

English EN

European Network for the Study of Adrenal Tumours - Structuring clinical research on adrenal cancers in adults

Objective

Among patients with adrenal masses Adrenocortical carcinoma (ACC) and malignant pheochromocytomas (MPH) are found with a low incidence but very unfavorable prognosis. Due to this poor clinical outcome, concomitant hormone dysregulation and limited treatment options the two cancer entities severely impact on affected patients. However, the rarity of the tumors also impedes clinical studies which are affected by fragmentation and low cohort sizes.
The European Network for the Study of Adrenal Tumors (ENS@T) has recently implemented a collection of adrenal tumor related databases and defined an associated network of Biological Resource Centers devoted to research on adrenal tumors. The concurrence of recent achievements of this evolving network, the progress in the understanding of molecular mechanisms and increasing availability of specific diagnostic and therapeutic tools for adrenal cancers provides the unique opportunity to achieve unmatched progress in the implementation of both translation and clinical research dedicated to ACC and MPH. Specifically, the newly formed ENS@T-CANCER consortium will address the following topics: 1. Structuring European clinical and translational research through implementation of a virtual research environment, 2. Improving clinical outcome of patients with adrenal cancer by conducting interventional trials carried out by European centers of excellence, 3. Improvement of differential diagnosis and risk stratification of adrenal cancer, 4. Identification and validation of tools for follow-up of patients with adrenal cancer, 5. Identification of novel biomarkers for treatment response.
The ultimate aim of the ENS@T-CANCER Consortium is to develop research in the field of adrenal cancers to improve diagnosis and treatment abilities. The Network will allow recruiting sufficient patients in all relevant European centers, to harmonize diagnosis criteria and to use the various technological approaches of a number of laboratories.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

Address

Geschwister Scholl Platz 1
80539 Muenchen

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 362 786

Administrative Contact

Felix Beuschlein (Prof.)

Participants (16)

Sort alphabetically

Sort by EU Contribution

Expand all

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

France

EU Contribution

€ 187 624

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

EU Contribution

€ 1 164 560

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Netherlands

EU Contribution

€ 385 000

UNIVERSITA DEGLI STUDI DI FIRENZE

Italy

EU Contribution

€ 49 800

FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III

Spain

EU Contribution

€ 483 830

THE UNIVERSITY OF BIRMINGHAM

United Kingdom

EU Contribution

€ 425 124

TECHNISCHE UNIVERSITAET DRESDEN

Germany

EU Contribution

€ 237 000

UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT

Germany

EU Contribution

€ 212 400

STICHTING KATHOLIEKE UNIVERSITEIT

Netherlands

EU Contribution

€ 283 200

UNIVERSITA DEGLI STUDI DI TORINO

Italy

EU Contribution

€ 866 000

INSTITUT GUSTAVE ROUSSY

France

EU Contribution

€ 434 432

UNIVERSITA DEGLI STUDI DI PADOVA

Italy

EU Contribution

€ 49 800

GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG

Germany

EU Contribution

€ 248 126

UNIVERSITY OF MELBOURNE

Australia

EU Contribution

€ 537 488

PHILIPPS UNIVERSITAET MARBURG

Germany

EU Contribution

€ 40 000

ARTTIC

France

EU Contribution

€ 26 808

Project information

Grant agreement ID: 259735

Status

Closed project

  • Start date

    1 January 2011

  • End date

    30 June 2016

Funded under:

FP7-HEALTH

  • Overall budget:

    € 8 137 566,52

  • EU contribution

    € 5 993 978

Coordinated by:

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

Germany