Skip to main content

Understanding food-gut-brain mechanisms across the lifespan in the regulation of hunger and satiety for health

Objective

Full4Health is a multidisciplinary European collaboration of internationally renowned laboratories investigating the mechanisms of hunger, satiety and feeding behaviour, effects of dietary components and food structure on these processes, and their possible exploitation in addressing obesity, chronic disease and under-nutrition. The proposal integrates investigation of both human volunteers (dietary/exercise intervention studies and administration of encapsulated nutrients) and laboratory animals with emphasis on neuronal, hormonal, molecular, physiological and psychological responses to food at different stages of the life course. We will apply imaging and other cutting edge technologies in both humans and rodents to answer critical research questions at different levels of the food-gut-brain axis. In human volunteers, responses to diet will be investigated from childhood through to the elderly, whereas wide-ranging cutting-edge rodent studies will investigate related issues such as early developmental programming the food-gut-brain axis, multiple feedback signalling interactions, and inflammation-induced anorexia. The project will examine the interaction of food and dietary components with the gastrointestinal tract, and will characterise the role of gut endocrine secretions, the vagus nerve, and hindbrain, hypothalamic and forebrain structures in signalling and integration of hunger and satiety. Physiological and psychological responses to food may change as we develop and age, with impact on food choices and preferences. This is a critical issue in the battle against food intake-related chronic disease, most commonly driven by over-consumption, but also in consideration of relative under-nutrition in the elderly and clinically compromised.

Call for proposal

FP7-KBBE-2010-4
See other projects for this call

Coordinator

UNIVERSITY OF ABERDEEN
Address
King's College Regent Walk
AB24 3FX Aberdeen
United Kingdom

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Elizabeth Rattray (Dr.)
EU contribution
€ 1 759 172

Participants (14)

CHAROKOPEIO PANEPISTIMIO
Greece
EU contribution
€ 577 263
Address
Eleftheriou Venizelou 70
17671 Athina

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Souliotis Jim (Mr.)
UNIVERSITY OF LEEDS
United Kingdom
EU contribution
€ 401 896
Address
Woodhouse Lane
LS2 9JT Leeds

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kathy Brownridge (Ms.)
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 1 091 388
Address
Heidelberglaan 100
3584 CX Utrecht

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Roger Adan (Prof.)
UNIVERSITEIT MAASTRICHT
Netherlands
EU contribution
€ 790 000
Address
Minderbroedersberg 4
6200 MD Maastricht

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
M.S. Westerterp-Plantenga (Prof.)
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 1 048 053
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Gaynor Hollander (Ms.)
GOETEBORGS UNIVERSITET
Sweden
EU contribution
€ 680 000
Address
Vasaparken
405 30 Goeteborg

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Emilia Rung (Dr.)
NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU
Norway
EU contribution
€ 349 801
Address
Hogskoleringen 1
7491 Trondheim

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Duan Chen (Dr.)
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 437 421
Address
Old College, South Bridge
EH8 9YL Edinburgh

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Angela Noble (Ms.)
Université Lille 2 Droit et Santé
France
EU contribution
€ 354 000
Address
Rue Paul Duez
59000 Lille

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marie Gompel (Dr.)
MW ENCAP LIMITED
United Kingdom
EU contribution
€ 143 458
Address
Station Road Old Station Works 1
SG86P2 Royston

See on map

Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Paul Higgins (Mr.)
KLINIKUM DER UNIVERSITAET ZU KOELN
Germany
EU contribution
€ 356 400
Address
Kerpener Strasse 62
50937 Koeln

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jens C. Bruening (Prof.)
KOBENHAVNS UNIVERSITET
Denmark
EU contribution
€ 355 080
Address
Norregade 10
1165 Kobenhavn

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ivan Kristoffersen (Mr.)
NUTRICIA RESEARCH BV
Netherlands
EU contribution
€ 71 750
Address
Uppsalalaan 12
3584 CT Utrecht

See on map

Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Klaske Van Norren (Dr.)
WAGENINGEN UNIVERSITY
Netherlands
EU contribution
€ 576 931
Address
Droevendaalsesteeg 4
6708 PB Wageningen

See on map

Activity type
Higher or Secondary Education Establishments
Administrative Contact
Tom Bessems (Mr.)