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Rationally Designed Aquatic Receptors integrated in label-free biosensor platforms for remote surveillance of toxins and pollutants

Objective

RADAR is a 7-member consortium that aims to develop a robust, sensitive, and versatile label-free, biosensor platform for spot measurements and on-line monitoring of toxins and pollutants in food production processes and in the aquatic environment.
Specificity towards chemical pollutants and toxins is achieved by using recombinant receptors (namely the estrogen receptor and the aryl hydrocarbon receptor) whose amino acid sequences have been rationally designed based on genomic and functional information from aquatic organisms.
Sensitivity of the biosensor is increased by the unique combination of isotachophoretic pre-concentration step, and surface nanostructuring & chemical modification.
The integration of the label-free detection sensors with an on-line automated sample handling and a wireless communication system will yield a best-in-class biosensor platform for robust, specific and sensitive detection of EDCs and PAHs in difficult operating conditions.
To validate the RADAR biosensor the consortium will test the biosensors in fresh and marine water, in fish farms, and in food products such as fish, fruit juices, and milk. Through their contacts in these industries, the partners will evaluate the performance of the biosensors in such environments, analyzing a representative number of samples and reporting on the stability, ruggedness and accuracy of the sensors used under laboratory and real test conditions.

This project is expected to have a high economic impact, since our cost-effective sensor could find a worldwide distribution in most food production and water testing lines as supported by Agilent Technologies Inc.

Field of science

  • /engineering and technology/environmental biotechnology/biosensing
  • /engineering and technology/electrical engineering, electronic engineering, information engineering/electronic engineering/sensors/biosensors
  • /engineering and technology/electrical engineering, electronic engineering, information engineering/information engineering/telecommunications/radio technology/radar
  • /natural sciences/chemical sciences/organic chemistry/amines
  • /social sciences/economics and business/economics/production economics

Call for proposal

FP7-KBBE-2010-4
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT
Address
Rue Jaquet Droz 1
2000 Neuchatel
Switzerland
Activity type
Research Organisations
EU contribution
€ 952 267
Administrative Contact
Peter Seitz (Prof.)

Participants (6)

JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION
Belgium
EU contribution
€ 802 650
Address
Rue De La Loi 200
1049 Brussels
Activity type
Research Organisations
Administrative Contact
Iain Formosa (Dr.)
OPTICS BALZERS AG
Liechtenstein
EU contribution
€ 277 210
Address
Neugrut 35
9496 Balzers
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Alex Vogt (Mr.)
FONDAZIONE PER L ISTITUTO DI RICERCA IN BIOMEDICINA
Switzerland
EU contribution
€ 284 387
Address
Via Vincenzo Vela 6
6500 Bellinzona
Activity type
Research Organisations
Administrative Contact
Giorgio Noseda (Prof.)
STICHTING WAGENINGEN RESEARCH
Netherlands
EU contribution
€ 313 662
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Activity type
Research Organisations
Administrative Contact
Jelte Zeilstra (Mr.)
Elysium Projects Limited
United Kingdom
EU contribution
€ 215 250
Address
Deiniol Road Unit 2, Mentec
LL57 2UP Bangor
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
John Bostock (Mr.)
NACIONALNI INSTITUT ZA BIOLOGIJO
Slovenia
EU contribution
€ 80 701
Address
Vecna Pot 111
1000 Ljubljana
Activity type
Research Organisations
Administrative Contact
Potocnik Franc (Mr.)