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Use of genomic and proteomic tools for the development of contaminant specific biomarkers for the environmental risk assessment of aquatic ecosystems

Objective

The use of genomic tools is rapidly increasing in ecotoxicology, and results from transcriptomic and proteomic studies of the effects of environmental pollutants are becoming more and more available. Apart from the knowledge of the mechanisms involved in toxic processes, the aim of conducting research on genomic and proteomic level is the development of contaminant specific biomarkers for the risk assessment of aquatic ecosystems able to respond at environmentally relevant low contaminant concentrations. However, even if important information is gathered on differential gene and proteome expression, the development of contaminant specific biomarkers in model organisms is still a task to be tackled. In this context, an attempt to joint efforts for the discovery and development of susceptible genes and proteins to be employed in routine environmental risk assessment is highly desirable. Several marine species from different organizational and trophic levels (the marine microalgae, Phaeodactylum tricornutum, and Cylindritheca closterium; the copepods Tisbe battagliai, Tigriopus japonicus, and Nitokra spinipes; the estuarine amphipod Melita plumulosa; the clam, Ruditapes decussates and the cockle Cerastoderma glaucum; the mussel Mytilus galloprovincialis; the oysters Crassostrea brasiliana, Crassostrea gigas and Crassostrea rhizophora; and the guppy, Poecilia vivipara) will be tested for the genomic and proteomic effects of the exposure to priority contaminants and the responses analyzed for similarities at different organizational levels with the aim to develop interspecies relevant biomarkers for environmental risk assessment of the most important contaminants, while at the same time transferring knowledge and experience by providing excellent training in cutting edge technologies between the participating institutes

Call for proposal

FP7-PEOPLE-2009-IRSES
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Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Address
Calle Serrano 117
28006 Madrid
Spain
Activity type
Research Organisations
EU contribution
€ 73 800
Administrative Contact
Carlos Manuel Abad Ruíz (Mr.)

Participants (4)

MUSEUM NATIONAL D'HISTOIRE NATURELLE
France
EU contribution
€ 30 600
Address
Rue Cuvier 57
75005 Paris
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Françoise Denis (Dr.)
UNIVERSIDADE DO ALGARVE
Portugal
EU contribution
€ 77 400
Address
Campus De Penha
8005 139 Faro
Activity type
Higher or Secondary Education Establishments
Administrative Contact
António Cabecinha (Mr.)
UNIVERSITE DU MANS
France
EU contribution
€ 70 200
Address
Avenue Olivier Messiaen
72085 Le Mans
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Claire Philippe (Ms.)
UNIVERSITAT DE VALENCIA
Spain
EU contribution
€ 30 600
Address
Avenida Blasco Ibanez 13
46010 Valencia
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Angeles Sanchis (Ms.)