Obiettivo A variety of complementary approaches are needed to evaluate safety of medicine use in pregnancy. To evaluate safety in relation to teratogenicity (capacity to cause malformations), population-based congenital anomaly registers, which are already networked across Europe (EUROCAT) with a common database, can provide a cost-effective mechanism which is as yet underexploited. The enormous population coverage of registers when combined gives sufficient statistical power for the identification of associations between specific drugs and specific malformations. This project will develop and test an efficient pharmaco-vigilance system for safety of drugs during pregnancy in relation to teratogenicity by (i) enhancing the information regarding drug exposure in the EUROCAT database, covering a total population of 3 million births 1995-2010, through linkage to electronic databases containing prescription information, and by linkage to chronic disease cohorts (ii) analysing the enhanced EUROCAT database in relation to four drug groups of public health concern - new antiepileptics, insulin analogs, SSRI antidepressants, and antiasthmatics - exposure to all of which is increasing in the pregnant population (iii) interrogating health care databases to monitor the effectiveness of drug safety recommendations and pregnancy prevention programmes through drug utilisation studies, and to provide an exposure profile for pregnant women (iv) conducting a scoping study of the implications for drug safety of growing internet use by pregnant women, in terms of access to safety information about teratogenicity, and access to drugs with teratogenic potential. Campo scientifico medical and health sciencesbasic medicinepharmacology and pharmacydrug safetymedical and health scienceshealth sciencespublic healthnatural sciencescomputer and information sciencesdatabases Programma(i) FP7-HEALTH - Specific Programme "Cooperation": Health Argomento(i) HEALTH.2010.4.2-3 - Adverse Drug Reaction Research. FP7-HEALTH-2010-single-stage Invito a presentare proposte FP7-HEALTH-2010-single-stage Vedi altri progetti per questo bando Meccanismo di finanziamento CP-FP - Small or medium-scale focused research project Coordinatore UNIVERSITY OF ULSTER Contributo UE € 1 093 379,95 Indirizzo CROMORE ROAD BT52 1SA Coleraine Regno Unito Mostra sulla mappa Regione Northern Ireland Northern Ireland Causeway Coast and Glens Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Anne Marie Patton (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (8) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto RIJKSUNIVERSITEIT GRONINGEN Paesi Bassi Contributo UE € 441 261,60 Indirizzo Broerstraat 5 9712CP Groningen Mostra sulla mappa Regione Noord-Nederland Groningen Overig Groningen Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Jan Poutsma (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITY OF BATH Regno Unito Contributo UE € 232 000,80 Indirizzo CLAVERTON DOWN BA2 7AY Bath Mostra sulla mappa Regione South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Bath and North East Somerset, North Somerset and South Gloucestershire Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Fiona Wallis (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato ACADEMISCH ZIEKENHUIS GRONINGEN Paesi Bassi Contributo UE € 242 976,40 Indirizzo HANZEPLEIN 1 9713 GZ Groningen Mostra sulla mappa Regione Noord-Nederland Groningen Overig Groningen Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo J J Breeuwsma (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato REGION SYDDANMARK Danimarca Contributo UE € 333 975,75 Indirizzo DAMHAVEN 12 7100 Vejle Mostra sulla mappa Regione Danmark Syddanmark Sydjylland Tipo di attività Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Contatto amministrativo Ester Garne (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU Polonia Contributo UE € 237 821,25 Indirizzo UL. FREDRY 10 61-701 Poznan Mostra sulla mappa Regione Makroregion północno-zachodni Wielkopolskie Miasto Poznań Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Bozena Raducha (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato CONSIGLIO NAZIONALE DELLE RICERCHE Italia Contributo UE € 155 823,00 Indirizzo PIAZZALE ALDO MORO 7 00185 Roma Mostra sulla mappa Regione Centro (IT) Lazio Roma Tipo di attività Research Organisations Contatto amministrativo Marco Borbotti (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato SWANSEA UNIVERSITY Regno Unito Contributo UE € 221 938,45 Indirizzo SINGLETON PARK SA2 8PP Swansea Mostra sulla mappa Regione Wales West Wales and The Valleys Swansea Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Julie Williams (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato QUEEN MARY UNIVERSITY OF LONDON Regno Unito Contributo UE € 36 922,80 Indirizzo 327 MILE END ROAD E1 4NS London Mostra sulla mappa Regione London Inner London — East Tower Hamlets Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Szendeffy Tanya (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
