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Development of a cost-effective anti-bacterial device for the 37 million urethral catheters used in enlarged Europe

Development of a cost-effective anti-bacterial device for the 37 million urethral catheters used in enlarged Europe

Objective

A survey conducted by WHO showed that 2,4 million of European patients suffer nosocomial infections every year. Urinary Tract Infections (UTI) account for approximately 40% of nosocomial infections; 80% of UTIs are associated with the use of indwelling urethral catheters. UTIs related to indwelling catheterisation prolong the mean length of hospitalisation, ranging from 2.4 to 19.8 days; 2 Billion Euro is the associated annual direct cost for National Health Services. Furthermore catheter associated UTIs are responsible for increased hospital mortality; the infection proves in fact fatal for around 30,000 people in Europe every year. Two routes of entry of uropathogens to catheterized urinary tracts exist: 1) extraluminal contamination may occur early, by direct inoculation when the catheter is inserted, or more frequently, by organisms ascending from the perineum by capillary action in the thin mucous film contiguous to the external catheter surface; 2) intraluminal contamination occurs by reflux of microorganisms gaining access to the catheter lumen from failure of closed drainage or contamination of urine in the collection bag. While extraluminal infection route was blocked by coating the external catheter walls with hydrogel-silver films that reproduce the natural barrier mechanism of urethra physiology, no effective solution exists today to avoid intraluminal infections. The overall objective of the project is to develop a cost-effective device able to create a barrier that avoids migration of the bacteria intraluminally. The proposed concept is based on a plastic cage whose internal walls are covered with a thin film of photocatalytic TiO2 (anatase), triggered by inexpensive low energy UV LEDs powered by coin cells commercially available for watches or calculators. The concept addresses the limitations of current approaches

Coordinator

RINA CONSULTING SPA

Address

Via San Nazaro 19
16145 Genova

Italy

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

EU Contribution

€ 37 280

Administrative Contact

Laura Giovanelli (Ms.)

Participants (7)

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B & V DI VANNUCCI CLAUDIA & C.SAS

Italy

EU Contribution

€ 387 308,80

MACIEJ I TADEUSZ POPIELAWSCY PIMETSJ

Poland

EU Contribution

€ 206 954

ELLA-CS sro

Czechia

EU Contribution

€ 109 583

EMOTEC SRL

Italy

EU Contribution

€ 364 933

BARCOVANLINE SRL

Italy

SKA POLSKA SP (ZOO)

Poland

FYZIKALNI USTAV AV CR V.V.I

Czechia

Project information

Grant agreement ID: 222164

Status

Closed project

  • Start date

    15 October 2008

  • End date

    14 October 2010

Funded under:

FP7-SME

  • Overall budget:

    € 1 485 325

  • EU contribution

    € 1 106 058,80

Coordinated by:

RINA CONSULTING SPA

Italy