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Systematic screening for novel hydrolases from hot environments

Systematic screening for novel hydrolases from hot environments

Objective

There is a strong need for new thermostable hydrolases with appropriate performance and/or novel functionalities that could provide huge savings in time, money and energy for industrial processes. The HotZyme project aims to identify such enzymes from hot terrestial environments, using metagenomic screening methods. New bioinfomatic tools will be developed to facilitate function prediction of genes from metagenomes that show low or no sequence homology to enzymes of known function. A range of high-throughput screening technologies will be employed to identify novel hydrolases. The consortium is composed of 13 partners from 10 European countries plus one partner from USA. The strong expertise in Microbiology, Moleculary Biology, Biochemistry, Biophysics, Geochemistry, Nanotechnology and Bioinformatics from our partners will be integrated in the project to ensure the fulfilment of the proposed tasks. Importantly, the five industrial partners, including three SMEs, will seek to commercialize the project results, thus ensuring a European wide impact, post project.
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Coordinator

KOBENHAVNS UNIVERSITET

Address

Norregade 10
1165 Kobenhavn

Denmark

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 207 873

Administrative Contact

Ivan Kristoffersen (Mr.)

Participants (12)

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MICRODISH BV

Netherlands

EU Contribution

€ 464 160

Montana State University Bozeman

United States

EU Contribution

€ 304 000

STIFTELSEN NORGES GEOTEKNISKE INSTITUTT

Norway

EU Contribution

€ 400 943

S.N. WINOGRADSKY INSTITUTE OF MICROBIOLOGY OF THE RUSSIAN ACADEMY OF SCIENCES

Russia

EU Contribution

€ 350 000

NOVOZYMES A/S

Denmark

EU Contribution

€ 396 032

WAGENINGEN UNIVERSITY

Netherlands

EU Contribution

€ 366 220

THE UNIVERSITY OF EXETER

United Kingdom

EU Contribution

€ 465 516

SIGMA-ALDRICH PRODUCTION GMBH

Switzerland

EU Contribution

€ 210 000

CONSIGLIO NAZIONALE DELLE RICERCHE

Italy

EU Contribution

€ 300 000

NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA

Greece

EU Contribution

€ 403 800

UNIVERSITAET DUISBURG-ESSEN

Germany

EU Contribution

€ 198 000

EUROPEAN CENTRE FOR RESEARCH & FINANCING LTD

Israel

EU Contribution

€ 452 000

Project information

Grant agreement ID: 265933

Status

Closed project

  • Start date

    1 April 2011

  • End date

    31 March 2015

Funded under:

FP7-KBBE

  • Overall budget:

    € 7 740 992

  • EU contribution

    € 5 518 544

Coordinated by:

KOBENHAVNS UNIVERSITET

Denmark