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Systematic screening for novel hydrolases from hot environments

Objective

There is a strong need for new thermostable hydrolases with appropriate performance and/or novel functionalities that could provide huge savings in time, money and energy for industrial processes. The HotZyme project aims to identify such enzymes from hot terrestial environments, using metagenomic screening methods. New bioinfomatic tools will be developed to facilitate function prediction of genes from metagenomes that show low or no sequence homology to enzymes of known function. A range of high-throughput screening technologies will be employed to identify novel hydrolases. The consortium is composed of 13 partners from 10 European countries plus one partner from USA. The strong expertise in Microbiology, Moleculary Biology, Biochemistry, Biophysics, Geochemistry, Nanotechnology and Bioinformatics from our partners will be integrated in the project to ensure the fulfilment of the proposed tasks. Importantly, the five industrial partners, including three SMEs, will seek to commercialize the project results, thus ensuring a European wide impact, post project.

Field of science

  • /engineering and technology/nanotechnology
  • /natural sciences/biological sciences/biophysics
  • /natural sciences/biological sciences/biochemistry
  • /natural sciences/biological sciences/microbiology
  • /natural sciences/earth and related environmental sciences/geochemistry
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes

Call for proposal

FP7-KBBE-2010-4
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

KOBENHAVNS UNIVERSITET
Address
Norregade 10
1165 Kobenhavn
Denmark
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 207 873
Administrative Contact
Ivan Kristoffersen (Mr.)

Participants (12)

MICRODISH BV
Netherlands
EU contribution
€ 464 160
Address
Schipholweg 275
1171 PK Badhoevedorp
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Martin Hessing (Dr.)
Montana State University Bozeman
United States
EU contribution
€ 304 000
Address
Montana Hall 309
59717 Bozeman
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Susan Couch (Ms.)
STIFTELSEN NORGES GEOTEKNISKE INSTITUTT
Norway
EU contribution
€ 400 943
Address
Sognsveien 72
N-0855 Oslo
Activity type
Other
Administrative Contact
Robert Nakken (Mr.)
S.N. WINOGRADSKY INSTITUTE OF MICROBIOLOGY OF THE RUSSIAN ACADEMY OF SCIENCES
Russia
EU contribution
€ 350 000
Address
Prospekt 60 Letiya Oktyabrya 7/2
117312 Moskva
Activity type
Research Organisations
Administrative Contact
Elizaveta Bonch-Osmolovskaya (Dr.)
NOVOZYMES A/S
Denmark
EU contribution
€ 396 032
Address
Krogshoejvej 36
2880 Bagsvaerd
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Nina Eckert Busgaard (Ms.)
WAGENINGEN UNIVERSITY
Netherlands
EU contribution
€ 366 220
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Tom Bessems (Mr.)
THE UNIVERSITY OF EXETER
United Kingdom
EU contribution
€ 465 516
Address
The Queen's Drive Northcote House
EX4 4QJ Exeter
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Clarke Enda (Dr.)
SIGMA-ALDRICH PRODUCTION GMBH
Switzerland
EU contribution
€ 210 000
Address
Industriestrasse 25
9470 Buchs
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Roland Wohlgemuth (Dr.)
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
EU contribution
€ 300 000
Address
Piazzale Aldo Moro 7
00185 Roma
Activity type
Research Organisations
Administrative Contact
Sergio Riva (Dr.)
NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA
Greece
EU contribution
€ 403 800
Address
Heroon Polytechniou 9 Zographou Campus
15780 Athina
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mertzelou Georgia (Ms.)
UNIVERSITAET DUISBURG-ESSEN
Germany
EU contribution
€ 198 000
Address
Universitatsstrasse 2
45141 Essen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Sandra Kramm (Ms.)
EUROPEAN CENTRE FOR RESEARCH & FINANCING LTD
Israel
EU contribution
€ 452 000
Address
Hamarva Street 15
30500 Binyamina
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Zohar Ben-Asher (Prof.)