Obiettivo This proposal addresses currently unresolved fundamental questions concerning the activation and functionalization in homogeneous catalysis of challenging, inherently unreactive substrates like NH3, CO2 or water. Responsive ligands in combination with earth-abundant first row transition metals may hold the key to selective bifunctional activation of these small molecules. This innovative, bioinspired concept, utilizing ligand-metal cooperativity to enhance, tune and control the reactivity of base metals, mimics and circumvents the use of expensive and/or toxic 2nd and 3rd row transition metals. A comprehensive tool-box of readily accessible smart ligand systems with cooperative, redox noninnocent or adaptive features will be used for stoichiometric and ultimately catalytic reactivity studies with Fe, Co, Ni and Cu. This will result in mechanistic understanding of novel pathways for selective N-H and O-H activation on well-defined mono- and dinuclear cooperative complexes. Coupling and insertion reactions with alkenes to yield efficient C-N and C-O bond forming processes and CO2 functionalization will be investigated. This fundamental knowledge is then applied for unprecedented cooperative catalysis with first row transition metals. The project will ultimately result in important leads for the direct intermolecular hydroamination of alkenes, including with ammonia, which is one of the top-ten challenges in catalysis, and the efficient, sustainable production of carboxylic acids from CO2 and alkenes. Also relevant contributions to the oxidative activation of water for hydration reactions with alkynes are foreseen. When successful, my initiatives will enable significant breakthroughs in the design of unique, smart ligand systems for the cooperative activation and functionalization of small molecules with base metals. An ERC starting grant greatly strengthens my position in the emerging field of cooperative homogeneous catalysis. Campo scientifico natural scienceschemical sciencesorganic chemistryorganic acidsnatural scienceschemical sciencescatalysissocial scienceseconomics and businesseconomicssustainable economy Programma(i) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) ERC-SG-PE5 - ERC Starting Grant - Materials and Synthesis Invito a presentare proposte ERC-2011-StG_20101014 Vedi altri progetti per questo bando Meccanismo di finanziamento ERC-SG - ERC Starting Grant Istituzione ospitante UNIVERSITEIT VAN AMSTERDAM Contributo UE € 1 498 471,00 Indirizzo SPUI 21 1012WX Amsterdam Paesi Bassi Mostra sulla mappa Regione West-Nederland Noord-Holland Groot-Amsterdam Tipo di attività Higher or Secondary Education Establishments Ricercatore principale Jarl Ivar Van Der Vlugt (Dr.) Contatto amministrativo Jo Lansbergen (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Beneficiari (1) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto UNIVERSITEIT VAN AMSTERDAM Paesi Bassi Contributo UE € 1 498 471,00 Indirizzo SPUI 21 1012WX Amsterdam Mostra sulla mappa Regione West-Nederland Noord-Holland Groot-Amsterdam Tipo di attività Higher or Secondary Education Establishments Ricercatore principale Jarl Ivar Van Der Vlugt (Dr.) Contatto amministrativo Jo Lansbergen (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato