Objective
"Meta Analyses of Heterogeneous Omics Data (MAHOD) will establish a framework in which data available in online repositories from previously performed Omics studies (i.e. metabolomics for analyses of small molecule metabolites in biofluids, proteomics for similar studies of proteins, etc.) will be analysed simultaneously using highly interpretable machine learning tools. These tools will reconcile differences in experimental design, demographic compositions, and modality (samples and variables that are not directly comparable). The ultimate goal of this research will be enable new insight into disease states and measure the statistical power based on the wealth of information and replicate samples available online. This will information will be exploitable by researchers in academia and industry, and will benefit the European Research Community by making better use of the data currently available for critical projects, and enable new research directions into diseases that are either poorly treatable or understood.
The framework will be evaluated by an analysis of existing data on a rare disease (narcolepsy), and a much more common disease (long COVID) to ensure that the technology scales from a relatively low volume of information, to a much more challenging ""big data"" problem.
This proposal will be carried out by an experienced researcher (ER) who completed their PhD in chemometrics, or the application of multivariate statistics and machine learning to chemical data. The ER is in a relatively unique position to bridge the gap between their knowledge of information and computer science, and domain knowledge related to the instrumentation required to perform Omics studies. The ER will be supervised by a computer scientist, who is an expert in the field of multivariate analysis and algorithm design."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine psychiatry sleep disorders
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
18071 GRANADA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.