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Content archived on 2024-06-18

Multicomponent Radiochemical reactions

Objective

The main focus of this research proposal is to diversify the portfolio of radiochemical reactions for the production of known and new 18F-radiotracers. The strategy we propose to investigate is based on the use of readily available 18F-labelled building blocks in the context of multicomponent reactions. This approach has the potential to deliver 18F-radiotracers not amenable to direct 18F-labelling due to poor reactivity or he unavailability of suitable reaction conditions. The project therefore concerns the development of various two-step synthetic sequences for the preparation of architecturally complex 18F-radiolabelled tracers applying sequences that will combine a nucleophilic 18F-fluorination process with a multicomponent reaction involving an 18F-labelled building block. The application of this unprecedented approach to the synthesis of radioactive biomarkers which are notoriously difficult to label by conventional methods will be investigated. This project will advance radiochemistry for molecular imaging and therefore indirectly contribute to improve human health.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-IIF-2008
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IIF - International Incoming Fellowships (IIF)

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
EU contribution
€ 177 948,70
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
United Kingdom

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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