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Comparative epidemiology of genetic lineages of Trypanosoma cruzi
ID: 223034
Anfangsdatum: 2009-01-01, Enddatum: 2012-12-31
The focus of this multidisciplinary proposal is to elucidate the epidemiology of the genetic lineages of T. cruzi, for improved understanding and prevention of Chagas disease. The project will unite skills in genotyping, genomics, genetics and pathogenesis in Europe with cons...
Programme: FP7-HEALTH
Record Number: 88960
Last updated on: 2017-05-25
Towards successful dengue control
ID: 517708
Anfangsdatum: 2005-11-01, Enddatum: 2009-10-31
Dengue, the most rapidly expanding viral disease in S-East Asia and Latin America, is a major neglected and uncontrolled disease. This project will provide new knowledge, tools and strategies in 3 key areas: 1. Improved knowledge of the immunopathology of severe dengue contrib...
Programme: FP6-INCO
Record Number: 78741
Last updated on: 2011-11-30
Transcriptional regulation and cellular localization of mycobacterial cell cycle proteins during dormancy
ID: 37566
Anfangsdatum: 2006-11-01, Enddatum: 2009-04-30
In this project we propose to study the relation between the cell cycle and dormancy development in Mycobacterium tuberculosis (Mtb). The final aim is to increase the knowledge on dormancy development and to identify potential candidates for the development of antitubercular...
Programme: FP6-LIFESCIHEALTH
Record Number: 85006
Last updated on: 2008-07-17
ID: IC18960079
Anfangsdatum: 1996-10-01, Enddatum: 1998-07-31
* To study the structure and kinetics of phosphofructokinase (PFK) and pyruvate kinase (PYK) of Leishmania, key enzymes in the metabolism of the parasite, and to determine differences with the corresponding mammalian enzymes. * To design and synthesize selective inhibitors of ...
Programme: FP4-INCO
Record Number: 33966
Last updated on: 2001-12-07
ID: IC18960027
Anfangsdatum: 1996-10-01, Enddatum: 1998-09-30
* To identify the domain of VP4 interacting with sialic acids. * To characterize the mechanism of membrane destabilization and pore formation. * To determine the viral protein(s) and/or domain(s) responsible for membrane destabilization. * To study the role of chaperones in fo...
Programme: FP4-INCO
Record Number: 34228
Last updated on: 2001-12-07
ID: IC18970220
Anfangsdatum: 1997-10-01, Enddatum: 2000-09-30
* to develop novel compounds active against human trypanosomiases and leishmaniasis; * to take advantage of an essential metabolism in these trypanosomatidae that glycolysis represents; * to design irreversible and quasi-irreversible inhibitors of glycolytic enzymes based on...
Programme: FP4-INCO
Record Number: 38251
Last updated on: 2001-12-07
ID: IC18970213
Anfangsdatum: 1998-01-01, Enddatum: 2000-12-31
* To define the kinetics and characteristics of infection, immune response and clinical evolution of Leishmania infantum infection in the dog, the main reservoir of visceral leishmaniasis. * To describe the natural history of canine leishmaniasis in inbred dogs, with emphasis...
Programme: FP4-INCO
Record Number: 40175
Last updated on: 2001-12-07
ID: IC18960084
Anfangsdatum: 1996-10-01, Enddatum: 1999-09-30
* To determine the mechanisms of action of alkyllysophospholipids (ALPs) against Leishmania and Trypanosoma cruzi , including effects on the host immune response * To identify novel biochemical and molecular targets in Leishmania and Trypanosoma * To establish ALP resistant cl...
Programme: FP4-INCO
Record Number: 33950
Last updated on: 2001-12-07
ID: IC18980371
Anfangsdatum: 1998-11-01, Enddatum: 2001-10-31
Programme: FP4-INCO
Record Number: 46494
Last updated on: 1999-03-11
ID: IC18980357
Anfangsdatum: 1998-11-01, Enddatum: 2002-10-31
Programme: FP4-INCO
Record Number: 46486
Last updated on: 1999-03-11
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List retrieved on: 2018-05-25
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