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ID: BIO4960493
Start date: 1996-09-01, End date: 1999-08-31
The main objective of this proposal is to generate and improve techniques for forced evolution of desired enzymatic activities. Two target enzymes 1. Savinase (subtilisin 309) and 2. Lipolase (H. lanuainosa Lipase) have been chosen for attempts to 1. change substrate specif...
Programme: FP4-BIOTECH 2
Record Number: 34553
Last updated on: 1996-12-12
ID: BIO4960580
Start date: 1996-09-01, End date: 1999-08-31
The filamentous fungus Trichoderma reesei produces two potent cellobiohydrolases, CBHI and CBHII. The two enzymes have different structures but both have active sites located in enclosed tunnels containing constellations of amino acids that interact with each other and the s...
Programme: FP4-BIOTECH 2
Record Number: 37544
Last updated on: 1997-07-17
ID: BIO4960189
Start date: 1996-04-01, End date: 1999-12-31
Programme: FP4-BIOTECH 2
Record Number: 31880
Last updated on: 1996-06-24
ID: BIO4960181
Start date: 1996-09-01, End date: 1999-11-30
In the last three years one of the most fundamental changes in our perception of microbial ecosystems, is the recognition that most bacteria have specialised cell to cell diffusible signalling systems (quorum) sensors) that allow them to constantly monitor their cell density...
Programme: FP4-BIOTECH 2
Record Number: 37581
Last updated on: 1997-07-17
The rhizosphere environment surrounding the root systems of all plants has a major influence on the health and productivity of crops. The composition of the rhizosphere microbial population often differs greatly from that of the surrounding soil, as a result of diverse plant m...
Programme: FP4-BIOTECH 2
Record Number: 23262
Last updated on: 1999-10-28
The research activities performed by the partners under the present project have led to synthesis and subsequent chemical and biological profiling of a novel class of immunosuppressive compounds. The compounds are water-soluble cyclic hexa-peptides of very facile chemical synt...
Programme: FP4-BIOTECH 2
Record Number: 27297
Last updated on: 2003-01-17
ID: BIO4980314
Start date: 1998-12-01, End date: 2001-05-31
Programme: FP4-BIOTECH 2
Record Number: 46732
Last updated on: 2001-12-07
Neue Immunosuppressions-Verbindungen verringern Nebenwirkungen
Immunosuppressiva sind klinisch wichtige Medikamente bei Organtransplantationen und zur Behandlung von Autoimmunerkrankungen. Jetzt gibt es eine neue Klasse von Immunosuppressions-Verbindungen, die sich durch niedrige Toxizität, hohe Spezifität und geringere Nebenwirkungen aus...
Programme: FP4-BIOTECH 2
Record Number: 80686
Last updated on: 2005-09-18
Available languages: DE, EN, ES, FR, IT
New immunosuppressive compounds suppress side effects
Immunosuppressants are clinically important for organ transplants and autoimmune diseases. A novel class of immunosuppressive compounds presents low toxicity, high specificity and fewer side effects.
Programme: FP4-BIOTECH 2
Record Number: 80686
Last updated on: 2005-09-18
Available languages: DE, EN, ES, FR, IT
De nouveaux composés immunosuppresseurs suppriment les effets secondaires
Sur le plan clinique, les immunosuppresseurs sont importants pour les transplantations d'organes et les maladies auto-immunes. Une nouvelle classe de composés immunosuppresseurs présente une faible toxicité, une spécificité élevée et peu d'effets secondaires.
Programme: FP4-BIOTECH 2
Record Number: 80686
Last updated on: 2005-09-18
Available languages: DE, EN, ES, FR, IT
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