Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Final Report Summary - MERIT (Mutanome Engineered RNA Immuno-Therapy)
The Mutanome Engineered RNA Immuno-Therapy (MERIT) project was funded by the European Commission under the 7th Framework Programme and ran from 2013 to 2017. A pioneering ribonucleic acid (RNA)-based immunotherapy approach to target individual tumor...
Programme: FP7-HEALTH
Record Number: 238068
Last updated on: 2018-07-26
Final Report Summary - TRANSLINK (Defining the role of xeno-directed and autoimmune events in patients receiving animal-derived bioprosthetic heart valves)
Much clinical evidence convincingly illustrates that, at least in theory, animal-derived bioprosthetic heart valves (BHV) represent the best treatment option for patients needing cardiac valve replacement. However, BHV are affected by premature failure due to structural valve...
Programme: FP7-HEALTH
Record Number: 237811
Last updated on: 2018-07-26
Periodic Report Summary 3 - HEPAVAC (Cancer Vaccine development for Hepatocellular Carcinoma)
Project Context and Objectives: PROBLEM: Hepatocellular carcinoma - HCC is a disease with high unmet medical need. Indeed, it accounts for about 6% of all new cancer cases diagnosed worldwide (nearly 750,000 new cases/year), and is the third and the fifth leading cause of...
Programme: FP7-HEALTH
Record Number: 237948
Last updated on: 2018-07-25
Periodic Report Summary 3 - ATHERO-B-CELL (Targeting and exploiting B cell functions for treatment in cardiovascular disease)
Project Context and Objectives: An experimental platform that permits the identification of mature B cell type(s) that either promote or prevent atherosclerosis and autoimmunity is lacking. Athero-B-Cell intends to identify differences in B cell effector subsets relevant to...
Programme: FP7-HEALTH
Record Number: 237961
Last updated on: 2018-07-25
Final Report Summary - HUMEN (Upscaling human insulin-producing beta cell production by efficient differentiation and expansion of endoderm progenitors)
1.0 Executive summary The specific scientific goal of HumEn was to overcome the scientific and technological hurdles in expanding human pluripotent stem cell (hPSC)-derived endodermal progenitors. The underlying rationale for this idea was that such development will contribute...
Programme: FP7-HEALTH
Record Number: 237975
Last updated on: 2018-07-25
Final Report Summary - E-PREDICE (Early Prevention of Diabetes Complications in people with Hyperglycaemia in Europe)
Background: Type 2 Diabetes (T2D) is a progressive chronic disease. Hyperglycaemia is related not only to macrovascular complications but also to many microvascular complications as retinopathy, nephropathy and peripheral neuropathy. According to WHO criteria `Intermediate...
Programme: FP7-HEALTH
Record Number: 237958
Last updated on: 2018-07-25
Periodic Report Summary 6 - EUROHYP-1 (European multicentre, randomised, phase III clinical trial of hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke)
Project Context and Objectives: The social and economic burdens of stroke are enormous. Stroke is the second cause of death in the European Union (EU), with over 500,000 deaths each year. Taking the EU27, Croatia, Iceland, Norway, and Switzerland together, Eurostat estimates...
Programme: FP7-HEALTH
Record Number: 237925
Last updated on: 2018-07-25
Final Report Summary - SYSVASC (Systems Biology to Identify Molecular Targets for Vascular Disease Treatment)
1.1. Executive Summary “Systems Biology to Identify Molecular Targets for Vascular Disease Treatment” (sysVASC) was a collaborative project based on established multidisciplinary European research networks, including specialists in pre-clinical and clinical research, omics...
Programme: FP7-HEALTH
Record Number: 237917
Last updated on: 2018-07-25
Periodic Report Summary 3 - MATHIAS (New Molecular-Functional Imaging Technologies and Therapeutic Strategies for Theranostic of Invasive Aspergillosis)
Project Context and Objectives: The development of novel technologies to diagnose and treat lung infections caused by the opportunistic fungal pathogen Aspergillus fumigatus is the aim of this European research consortium. Invasive pulmonary aspergillosis (IPA) is a...
Programme: FP7-HEALTH
Record Number: 238043
Last updated on: 2018-07-25
Periodic Report Summary 3 - ATHERO-FLUX (Targeting novel lipid pathways for treatment of cardiovascular disease)
Project Context and Objectives: Cardiovascular disease (CVD) causes much of the disease burden in Europe, claiming each year 4.3 million lives in Europe, 2.0 million in the EU (European Heart Network; www.ehnheart.org). The main forms of CVD are coronary artery disease (CAD)...
Programme: FP7-HEALTH
Record Number: 238106
Last updated on: 2018-07-25
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List retrieved on: 2018-08-22
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