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High-throughput, fully automated and cost-effective behavioural phenotyping of normal, clinical and genetic mouse models
ID: 37965
Start date: 2006-11-01, End date: 2009-10-31
Behavioural change is the most sensitive biological end-point signalling any alteration in the organism of a mouse. However, large-scale bio-assays of behaviour face limitations: outdated technology, need for space and specialized manpower, lack of standardisation, and increas...
Record Number: 93061
Last updated on: 2013-03-26
ID: 37554
Start date: 2007-01-01, End date: 2009-12-31
Glutamate is the most abundant excitatory transmitter in the brain. However, very few models exist to explore the potential of drugs that modulate glutamate transmission. Because altered glutamate transmission is involved in numerous psychiatric diseases, there is a strong nee...
Record Number: 96574
Last updated on: 2013-03-26
A large scale genome-wide association study of schizophrenia addressing variation in expressivity and contribution from environmental factors
ID: 37761
Start date: 2006-11-01, End date: 2010-04-30
Schizophrenia (SZ) is a complex and disabling disorder that continues to exact a heavy toll not only upon those afflicted but also on relatives and on our health and welfare systems. Family history significantly increases the risk of developing the disease and evidence from ep...
Record Number: 93358
Last updated on: 2013-03-26
Innovation, coordination and collaboration in service driven manufacturing supply chains
ID: 17192
Start date: 2005-10-01, End date: 2008-03-31
The European manufacturing industry strongly relies on external services & consumes nearly 30 % of the intermediate output of business related services. Despite this, service providers & customers are facing tremendous problems in synchronizing the business processes & facilit...
Programme: FP6-NMP
Record Number: 93677
Last updated on: 2012-03-13
Identification of early disease markers, novel pharmacologically tractable targets and small molecule phenotypic modulators in Huntington's Disease'
ID: 37472
Start date: 2007-01-01, End date: 2010-12-31
Huntington's is a devastating neurodegenerative disease with many unmet patient needs. There are no known ways of slowing or preventing the neuro-degeneration, and clinical trials in man are hampered by the slow disease progression and the absence of suitable biomarkers of sho...
Programme: FP6-IST
Record Number: 96397
Last updated on: 2011-01-24
Development of flash photolysis for deep uncaging in vivo and high throughput characterisation of neurotransmitter gated ion channels in drug discovery
ID: 37765
Start date: 2007-03-01, End date: 2010-08-31
Flash photolysis is widely applied in cell physiology to initiate neurotransmitter and other ligand'receptor interactions in conditions that are subject to poor diffusional access and receptor desensitisation, and for labile ligands. It has the potential to initiate reactions ...
Programme: FP6-IST
Record Number: 93937
Last updated on: 2010-08-31
European project on the characterisation of transgenic rat models for neurodegenerative and psychiatric diseases: Automated home cage analyses, live imaging and treatment
ID: 37846
Start date: 2007-01-01, End date: 2010-06-30
The RATstream' consortium will concentrate on the comprehensive phenotypical characterization of rat models of neurodegenerative diseases such as Huntington's disease (HD), Parkinson's disease (PD) and spinocerebellar ataxia type 17 (SCA17). Ultimately, the project will delive...
Programme: FP6-IST
Record Number: 95215
Last updated on: 2010-07-20
Radically Innovative Mechatronics and Advanced Control Systems
ID: 16938
Start date: 2005-09-01, End date: 2008-08-31
The present global competitive environment poses formidable challenges to the European manufacturing infrastructure; among others, we single out speed in responding to continuously changing market demands, time-to-market pressure, plant and equipment costs, and the need of amo...
Programme: FP6-NMP
Record Number: 74893
Last updated on: 2007-10-03
A knowledge-based manufacturing system, established by integrating Rapid Manufacturing, IST and Material Science to improve the Quality of Life of European Citizens through Custom fit Products.
ID: 507437
Start date: 2004-09-01, End date: 2009-02-28
European manufacturing industries have to compete with Far East countries. In recent years, approx. 5% of the turnover from this sector has moved from the EU to the Far East, per annum. This EU sector realises a 1,200 billion Euro turnover with a workforce of 24 million people...
Programme: FP6-NMP
Record Number: 74427
Last updated on: 2005-05-24
List retrieved on: 2018-03-19
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