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FP7-IDEAS-ERC (11)

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Improved Cryopreservation using Ice Binding Proteins
ID: 281595
Start date: 2011-11-01, End date: 2016-10-31
Several organisms have evolved specialized ice binding proteins (IBPs) that prevent their body fluids from freezing (antifreeze proteins, AFPs), inhibit recrystallization of ice in frozen tissues, or initiate freezing at moderate supercooling temperatures (ice nucleating prot...
Programme: FP7-IDEAS-ERC
Record Number: 101006
Last updated on: 2017-07-02
Host molecular and cellular responses to anti-cancer drug treatment as a potential biomarker for treatment outcome
ID: 260633
Start date: 2011-03-01, End date: 2017-02-28
Chemotherapy remains one of the most common treatment modalities for cancer. It is typically administered in cycles of bolus injections following 21 days of drug-free break periods. However, tumor regrowth between drug intervals is often observed, due in part, to rebound angi...
Programme: FP7-IDEAS-ERC
Record Number: 103604
Last updated on: 2017-05-29
Development of an accessible platform for  ex vivo site specific post-translational modifications of proteins
ID: 260647
Start date: 2010-10-01, End date: 2016-03-31
The incorporation of unnatural amino acids (more than 50 to date) into proteins in vivo has resulted in the generation of proteins with novel chemical, biological, and physical properties. However, some unnatural amino acids possess properties, such as an inability to cross t...
Programme: FP7-IDEAS-ERC
Record Number: 96277
Last updated on: 2017-05-29
Tracking and Targeting a T-DNA Vector for Precise Engineering of Plant Genomes
ID: 268646
Start date: 2011-05-01, End date: 2016-04-30
DNA introduced into a cell usually integrates, if at all, at random in the genome. In order for gene targeting to take place, a small vector must scan a huge genome that is packaged in chromatin, identify and bind the target, and engage in strand exchange. This formidable tas...
Programme: FP7-IDEAS-ERC
Record Number: 98705
Last updated on: 2017-05-26
Microfabrication-Based Rational Design of Transcriptional-Metabolic Intervention for the Treatment of Hepatitis C Virus (HCV) Infection
ID: 242699
Start date: 2010-04-01, End date: 2015-03-31
Hepatitis C Virus (HCV) infection affects over 3% of the world population and is the leading cause of chronic liver disease worldwide. Current treatments are effective in only 50% of the cases and associated with significant side effects. Therefore, there is a pressing need f...
Programme: FP7-IDEAS-ERC
Record Number: 92124
Last updated on: 2017-05-25
Biomolecular computers
[PROJECT] BIOMOLECULAR_COMP - Biomolecular computers
ID: 233047
Start date: 2009-01-01, End date: 2013-10-31
Autonomous programmable computing devices made of biological molecules hold the promise of interacting with the biological environment in future biological and medical applications. Our laboratory's long-term objective is to develop a 'Doctor in a cell': molecular-sized devic...
Programme: FP7-IDEAS-ERC
Record Number: 89085
Last updated on: 2017-05-25
Synthetic Biology Approach to Adhesion-Mediated Environmental Sensing
ID: 294852
Start date: 2012-05-01, End date: 2018-04-30
The primary aims of this work are tightly connected: (i) development of a bio-inspired “synthetic cell” capable of self-assembling, self-propelling and environmental sensing prepared with reduced molecular complexity compared to living cells (ii) quantitative assessment of th...
Programme: FP7-IDEAS-ERC
Record Number: 103592
Last updated on: 2016-10-10
Is there a limit to yield?
[PROJECT] YIELD - Is there a limit to yield?
ID: 294691
Start date: 2012-01-01, End date: 2016-12-31
Plant breeders are challenged with sustaining global crop improvements. Is there a limit to crop yield? This project will address this central question using processing tomatoes as a model for a mechanized crop. By integrating in a single web-based platform of ‘Phenom Network...
Programme: FP7-IDEAS-ERC
Record Number: 101836
Last updated on: 2016-09-05
Harnessing the Dark Side of Protein Folding: Manipulating Aggregation for Recombinant Protein Production
ID: 337713
Start date: 2013-11-01, End date: 2018-10-31
Nearly all desirable biological activities, whether for the purposes of nutrition, pharmacology, biofuel production, or waste disposal, can be carried out by proteins. Nature has furnished a vast array of bioactive and biocatalytic tools, and with the advent of rational prote...
Programme: FP7-IDEAS-ERC
Record Number: 110664
Last updated on: 2016-08-29
Harnessing Oxygenic Photosynthesis for Sustainable Energy Production
ID: 293579
Start date: 2012-01-01, End date: 2017-12-31
Oxygenic photosynthesis, that takes place in cyanobacteria algae and plants, provides most of the food and fuel on earth. The light stage of this process is driven by two photosystems. Photosystem II (PSII) that oxidizes water to O2 and 4 H+ and photosystem I (PSI) which in t...
Programme: FP7-IDEAS-ERC
Record Number: 101526
Last updated on: 2016-04-12
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List retrieved on: 2018-05-28
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