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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 3235
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Factor XII and the contact system: 
cross-talk between thrombosis and inflammation
ID: 311575
Start date: 2013-08-01, End date: 2018-07-31
Combinations of proinflammatory and procoagulant reactions are the unifying principle for a variety of disorders affecting the cardiovascular system. Factor XII (FXII, Hageman factor) is a plasma protease that initiates the contact system. This system starts a cascade of proc...
Programme: FP7-IDEAS-ERC
Record Number: 109422
Last updated on: 2018-01-22
Next generation sequencing for detection of human primary immunodeficiency syndromes characterized by impaired cytotoxic lymphocyte function
ID: 311335
Start date: 2013-05-01, End date: 2018-04-30
Human primary immunodeficiencies affecting cytotoxic lymphocyte function are associated with high morbidity and mortality. They often present as hyperinflammatory syndromes triggered by viral infections, hematological malignancies, or systemic autoimmunity. Although recent ad...
Programme: FP7-IDEAS-ERC
Record Number: 108234
Last updated on: 2018-01-22
Hypothalamic Lipotoxicity and Endoplasmic Reticulum Stress: a New Pathophysiological Mechanism of Obesity
ID: 281854
Start date: 2011-12-01, End date: 2017-05-31
It is well established that metabolically relevant organs such as adipose tissue, pancreatic beta cells, liver and skeletal muscle develop endoplasmic reticulum (ER) stress under conditions of obesity induced lipotoxicity. Here, the applicant will investigate if/how the hypot...
Programme: FP7-IDEAS-ERC
Record Number: 100682
Last updated on: 2018-01-22
Disarming bacterial weapons in the nucleus:
functional study of Chlamydia nuclear effectors
ID: 282046
Start date: 2012-07-01, End date: 2018-06-30
The high prevalence of Chlamydia infections and the heavy burden they inflict on public health justify the search for novel therapeutic approaches directed against this pathogen. Research on this obligate intracellular bacterium is very difficult, due to substantial technical...
Programme: FP7-IDEAS-ERC
Record Number: 103960
Last updated on: 2018-01-15
p53 as a New Mediator of Energy Balance in the Brain
ID: 281408
Start date: 2011-12-01, End date: 2017-05-31
p53 is a transcriptional factor modulating numerous biological actions. Although it is best known for its role in cancer development, it is now evident that it is implicated in metabolism. More specifically, p53 modulates energy metabolism and homeostasis through their effect...
Programme: FP7-IDEAS-ERC
Record Number: 100931
Last updated on: 2018-01-03
European Consortium for Communicating Stem Cell Research
ID: 241878
Start date: 2010-03-01, End date: 2015-02-28
The European Consortium for Communicating Stem Cell Research, EUROSTEMCELL, brings together the major current FP6 and FP7 stem cell projects, the European Clinical Research Infrastructure Network, and four internationally recognized European stem cell centres to develop a com...
Programme: FP7-HEALTH
Record Number: 94445
Last updated on: 2018-01-03
Priming of plant immunity: from its onset to trans-generational maintenance
ID: 309944
Start date: 2013-01-01, End date: 2017-12-31
Plant defence depends on speed: the sooner a plant recognises its attacker, the more effective its defence response will be. Over the course of evolution, plants have acquired the ability to prime their immune system after perception of specific environmental signals. This he...
Programme: FP7-IDEAS-ERC
Record Number: 104861
Last updated on: 2017-12-18
Yeast symbionts of malaria vectors: from basic research to the management of malaria control
ID: 281222
Start date: 2012-06-01, End date: 2017-05-31
Advances in biotechnology propose innovative tools particularly relevant for public health application by genetic manipulation of microbial symbionts of arthropod vectoring disease. The symbiont engineering prevents the transmission of pathogens to human by interfering with t...
Programme: FP7-IDEAS-ERC
Record Number: 103726
Last updated on: 2017-12-18
Pathogenesis and transmission of influenza virus in pigs
ID: 258084
Start date: 2010-07-01, End date: 2014-12-31
FLUPIG aims at a better understanding of the role of pigs in influenza pandemics. Pandemic influenza viruses come from wild birds, but they must adapt to efficient replication and transmission in humans to cause a pandemic. Pigs are considered important intermediate hosts in ...
Programme: FP7-KBBE
Record Number: 95874
Last updated on: 2017-12-11
Engineering an artificial immune system with functional components assembled from prokaryotic parts and modules
ID: 322797
Start date: 2013-05-01, End date: 2019-04-30
The objective of this project is to overcome current limitations for antibody production that are inherent to the extant immune system of vertebrates. This will be done by creating an all-in-one artificial/synthetic counterpart based exclusively on prokaryotic parts, devices ...
Programme: FP7-IDEAS-ERC
Record Number: 107706
Last updated on: 2017-12-07
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List retrieved on: 2018-04-25
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