Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 108
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A radical approach for improved glaucoma treatment
ID: 322656
Start date: 2013-04-01, End date: 2018-09-30
Open angle glaucoma (OAG) is the second leading cause of world blindness. Treatments involving topically applied pressure-reducing medications or surgery targeting ocular drainage channels are effective, although significant complications exist. We propose to address the hypo...
Programme: FP7-IDEAS-ERC
Record Number: 107669
Last updated on: 2018-01-08
Novel vaccine generation for the treatment of cancer. A glyco-nanomedial approach instructing T cells
ID: 339977
Start date: 2014-02-01, End date: 2019-07-31
There is an urgent need to develop vaccines for the induction of CD8+ T-cell immunity to treat cancer and infectious diseases. Dendritic Cells (DC) have shown potential to induce antigen specific CD8+ T-cell responses with the help of CD4+ T cells, yet the efficacy by which t...
Programme: FP7-IDEAS-ERC
Record Number: 192378
Last updated on: 2017-12-18
Identification and functional validation of drugable targets/pathways for triple negative breast cancer
ID: 322737
Start date: 2013-04-01, End date: 2018-03-31
Patients suffering from triple-negative breast cancer (TNBC) have a poor prognosis as these tumors frequently confer resistance against chemotherapeutic agents and lack drug targets such as estrogen receptor, progesterone receptor, and epidermal growth factor receptor 2. Insu...
Programme: FP7-IDEAS-ERC
Record Number: 108208
Last updated on: 2017-12-18
Novel Tools for Early Childhood Predisposition to Obesity
ID: 293574
Start date: 2012-09-01, End date: 2018-08-31
An estimated 22 million children worldwide under age five are overweight. In these children, obesity is a primary indicator for development of type 2 diabetes and possibly cancer. I present a research program, SELECTionPREDISPOSED, to identify novel obesity-risk genes as tool...
Programme: FP7-IDEAS-ERC
Record Number: 103540
Last updated on: 2017-12-04
Randomized controlled trial of metformin and dietary restriction to prevent age-related morbid events in people with  metabolic syndrome
ID: 322752
Start date: 2013-08-01, End date: 2019-07-31
Age–related chronic diseases (ArCD) are complex non-linear processes that depends on a large number of interconnected genetic and metabolic pathways which should be tackled with a many faceted preventive strategy. Calorie-dense diet and sedentary lifestyle are responsible of ...
Programme: FP7-IDEAS-ERC
Record Number: 108844
Last updated on: 2017-11-20
Individualized early risk assessment for heart diseases
ID: 340248
Start date: 2014-06-01, End date: 2019-05-31
Heart failure (HF) is the common end-stage of different medical conditions. It is the only growing cardiovascular disease and its prognosis remains worse than that of many malignancies. The lack of evidence-based treatment for patients with diastolic HF (HFpEF) exemplifies th...
Programme: FP7-IDEAS-ERC
Record Number: 188503
Last updated on: 2017-11-20
Identification and targeting of somatic changes initiating sporadic cancers
ID: 322602
Start date: 2013-03-01, End date: 2018-02-28
Cancer drugs are extremely ineffective, generally because current therapies do not address cellular heterogeneity. While hypothesis-driven research and functional genomics identify ever more novel putative therapeutic targets, the scientific community lacks rationales to atta...
Programme: FP7-IDEAS-ERC
Record Number: 107221
Last updated on: 2017-11-20
A New Paradigm for Public Health Surveillance: Unlocking the Potential of Data to Empower Women and Health Systems
ID: 617639
Start date: 2014-09-01, End date: 2019-08-31
Rationale: State of the art health registries, cornerstones of public health surveillance, have hardly capitalized on the information and communication technology revolution. Many continue to be static, fragmented, and passive data repositories disseminating outdated reports ...
Programme: FP7-IDEAS-ERC
Record Number: 192003
Last updated on: 2017-11-20
Lymphocyte microRNAs in health and disease: Understanding lymphocyte functions through the identification of microRNA target genes and exploiting serum microRNA signatures to monitor immune responses
ID: 269022
Start date: 2011-06-01, End date: 2016-05-31
Background: CD4+ T lymphocyte subsets orchestrate immune responses in health and disease. Little is known on control of T cell differentiation exerted by microRNA that affect mRNA translation. The identification of microRNA and their targets that regulate differentiation of T...
Programme: FP7-IDEAS-ERC
Record Number: 99074
Last updated on: 2017-11-20
A Novel Non-Invasive Prenatal Diagnosis for Genetic Disorders
ID: 322953
Start date: 2013-05-01, End date: 2019-04-30
Non-Invasive Prenatal Diagnosis (NIPD) has been one of the most fascinating research fields during the last decade. The identification of small amounts of fetal DNA in maternal circulation has opened new possibilities for NIPD. Up until today, two methods have achieved accura...
Programme: FP7-IDEAS-ERC
Record Number: 108353
Last updated on: 2017-10-06
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List retrieved on: 2018-03-22
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