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Cerca progetti e risultati

Results 1 - 10 of 13017
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Factor XII and the contact system: 
cross-talk between thrombosis and inflammation
ID: 311575
Data di inizio: 2013-08-01, Termine: 2018-07-31
Combinations of proinflammatory and procoagulant reactions are the unifying principle for a variety of disorders affecting the cardiovascular system. Factor XII (FXII, Hageman factor) is a plasma protease that initiates the contact system. This system starts a cascade of proc...
Programme: FP7-IDEAS-ERC
Record Number: 109422
Last updated on: 2018-01-22
Next generation sequencing for detection of human primary immunodeficiency syndromes characterized by impaired cytotoxic lymphocyte function
ID: 311335
Data di inizio: 2013-05-01, Termine: 2018-04-30
Human primary immunodeficiencies affecting cytotoxic lymphocyte function are associated with high morbidity and mortality. They often present as hyperinflammatory syndromes triggered by viral infections, hematological malignancies, or systemic autoimmunity. Although recent ad...
Programme: FP7-IDEAS-ERC
Record Number: 108234
Last updated on: 2018-01-22
Hypothalamic Lipotoxicity and Endoplasmic Reticulum Stress: a New Pathophysiological Mechanism of Obesity
ID: 281854
Data di inizio: 2011-12-01, Termine: 2017-05-31
It is well established that metabolically relevant organs such as adipose tissue, pancreatic beta cells, liver and skeletal muscle develop endoplasmic reticulum (ER) stress under conditions of obesity induced lipotoxicity. Here, the applicant will investigate if/how the hypot...
Programme: FP7-IDEAS-ERC
Record Number: 100682
Last updated on: 2018-01-22
Integrated Monitoring and Control of Foodborne Viruses in European Food Supply Chains
ID: 213178
Data di inizio: 2008-04-01, Termine: 2011-09-30
The concept of VITAL is the integrated monitoring and control of contamination of the European food supply chain by pathogenic viruses. VITAL will use advanced methods for virus detection throughout selected food supply chains from farm to market, to gather data on virus cont...
Programme: FP7-KBBE
Record Number: 88416
Last updated on: 2018-01-22
Comparing the effectiveness of palliative care for elderly people in long term care facilities in Europe
ID: 603111
Data di inizio: 2014-02-01, Termine: 2019-01-31
Aging populations, rising costs and sustainable delivery of high-quality care are increasingly common concerns in all EU countries. PACE aims to perform comparative effectiveness research concerning palliative care in long term care facilities (LTCFs) in Europe. While a growi...
Programme: FP7-HEALTH
Record Number: 110075
Last updated on: 2018-01-15
Disarming bacterial weapons in the nucleus:
functional study of Chlamydia nuclear effectors
ID: 282046
Data di inizio: 2012-07-01, Termine: 2018-06-30
The high prevalence of Chlamydia infections and the heavy burden they inflict on public health justify the search for novel therapeutic approaches directed against this pathogen. Research on this obligate intracellular bacterium is very difficult, due to substantial technical...
Programme: FP7-IDEAS-ERC
Record Number: 103960
Last updated on: 2018-01-15
A radical approach for improved glaucoma treatment
ID: 322656
Data di inizio: 2013-04-01, Termine: 2018-09-30
Open angle glaucoma (OAG) is the second leading cause of world blindness. Treatments involving topically applied pressure-reducing medications or surgery targeting ocular drainage channels are effective, although significant complications exist. We propose to address the hypo...
Programme: FP7-IDEAS-ERC
Record Number: 107669
Last updated on: 2018-01-08
Dynamics of human genome architecture in stable and transient gene expression changes
ID: 609989
Data di inizio: 2014-06-01, Termine: 2019-05-31
The classical view of genomes as linear sequences has been replaced by a vision of nuclear organization that is both dynamic and complex, with chromosomes and genes non-randomly positioned in the nucleus. Process compartmentalization and spatial location of genes modulate the...
Programme: FP7-IDEAS-ERC
Record Number: 191292
Last updated on: 2018-01-03
Updating the mind: The mechanisms behind behavioural change
ID: 312445
Data di inizio: 2013-02-01, Termine: 2018-01-31
Translation of basic research on human executive control into facilitating behavioural change is a holy grail for psychologists and neuroscientists. Adaptive behaviour is attributed to executive functions that update the cognitive system. But how system updating mechanisms re...
Programme: FP7-IDEAS-ERC
Record Number: 105964
Last updated on: 2018-01-03
Bioactivated hierarchical hydrogels as zonal implants for articular cartilage regeneration
ID: 309962
Data di inizio: 2013-01-01, Termine: 2017-12-31
Degeneration of cartilage is a major cause of chronic pain, lost mobility and reduced quality of life for millions of European citizens. From a clinical point of view treatment to achieve cartilage regeneration (hyaline) and not only repair (fibrous) remains a great challenge...
Programme: FP7-NMP
Record Number: 106543
Last updated on: 2018-01-03
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List retrieved on: 2018-02-22