Community Research and Development Information Service - CORDIS


Periodic Report 1 - NANOPHOTO (Targeted Nanosystems for improving photodynamic therapy and diagnosis of cancer)

Project ID: 201031
Funded under: FP7-HEALTH


This is the periodic report of the NANOPHOTO project whose ambitious objective was the engineering of a nanosystem-based formulation able to guarantee efficient and selective delivery for meta-tetrahydroxyphenyl chlorine (mTHPC) to cancer cells and diminish the side effects of photodynamic therapy (PDT) therefore making the treatment more acceptable to the patients.

The report reveals that studies carried out so far have produced new mTHPC liposomal formulations that improve substantially and from various points of view, the treatment of cancer with PDT. Further improvements are expected during the second period of the project which may arise from additional in vivo pharmacokinetics and PDT studies and / or from conjugation of the nanocarriers to tumour cell specific ligands.

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