Community Research and Development Information Service - CORDIS


Final Report - PULMOTENSION (Pulmonary Hypertension: Functional Genomics and Therapy of Lung Vascular Remodelling)

Project ID: 18725


This is the final report for PULMOTENSION project. Funded under the European Commission's Sixth Framework Programme (FP6), PULMOTENSION has characterised a number of different molecular mechanisms underlying the dramatic remodelling processes in the lung vasculature, which result in an increase in vascular resistance by more than one order of magnitude. To this end, genetics, functional genomics, and proteomics have been combined with cell culture studies, experimental pulmonary hypertension animal models, and analysis of clinical tissue bank material.

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