Community Research and Development Information Service - CORDIS


Final Report - DELIVER (Design of Effective and sustainable control strategies for LIVER fluke in Europe)

Project ID: 23025
Funded under: FP6-FOOD


Liver fluke disease, or fascioliasis, affects an estimated 17 million people worldwide, particularly in Andean America, Africa and Asia. In ruminants, fascioliasis has dramatically increased in the EU in recent years, causing annual livestock losses of EUR 60 million in Ireland alone. DELIVER was set up with the aim of developing new environment-friendly methods for the control of the disease in livestock, thereby minimising the use of anthelmintic drugs and enhancing the quality and safety of meat and dairy products.

The aim of the work in this package was to improve our understanding of the epidemiology of fascioliasis by determining the farm-specific risk factors for infection, improving the sensitivity of diagnosis of patent infection and improving our understanding of how genetic variation in populations of fluke affect their interaction with the intermediate snail host and their infectivity and pathogenicity for farmed livestock.

Their final report covers their research, which covers forecasting, vaccine development and drug resistance studies, but the overall disease control process faces other challenges. There is evidence that climate change, bringing warmer and wetter spring and summer seasons, is increasing the incidence of the infection and spreading it to areas previously unaffected.

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