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Final Report - MILD-TB (Immunogenicity of Mycobacterium tuberculosis lipids in the non replicating status of latency)

Project ID: 37326


This is the final report for the MILD-TB project. The aim of this project was to produce new knowledge and insight that bear a potential for new therapeutic or prophylactic interventions focusing on one of the most critical immune evasion mechanism of Mycobacterium tuberculosis (Mtb): the capacity to switch to a dormant status of latency, which causes its persistence in the host.

As outlined in the project's final report, MILD-TB has analysed the immunogenicity of lipids isolated from non-replicating Mtb produced in vitro using a culture method resembling Mtb dormancy in vivo.

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