Servicio de Información Comunitario sobre Investigación y Desarrollo - CORDIS


Final Report - VITAL (Development of optimized recombinant idiotypic vaccines for subset-specific immunotherapy of B cell lymphomas)

Project ID: 37874


This is the final report for the VITAL project which aimed at the development and production of optimised recombinant Id vaccines for the immunotherapeutic treatment of distinct subset of B cell lymphomas and leukemias. According to the report, the most innovative aspect of the VITAL project was constituted by the idea to exploit the molecular features of Id proteins of distinct B cell lymphomas / leukemias, particularly those pathogenically associated with a chronic antigenic stimulation, to develop pre-made, recombinant Id proteins to vaccinate subgroups of lymphoproliferative disorders expressing molecularly correlated idiotypes. It also details the patents filed as a result of their work.

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