This document aims at presenting the NANOFUTURES integrated research and innovation roadmap for 2013-2025, including detailed implementation plan focusing more on actions up to 2020. This roadmap represents an open working document, developed within the European Coordination and Support Action NANOFUTURES (contract number: NMP4-CA-2010-266789). This document will be further developed with all NANOFUTURES platform members and other stakeholders from the nano-related community who would like to contribute.