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Final Report - ADAMNEURON (Study and Identification of ADAM10 as Neuronal a-secretase in relation to Alzheimer’s disease)

Project ID: 224847
Funded under: FP7-PEOPLE


This is the final report of ADAMNEURON project funded under the European Union (EU)-funded framework programme (FP) seven. The overall goal of this proposal was to determine whether the metalloprotease and major alpha-secretase candidate ADAM10, is indeed responsible for beta-secretase activity in neurons, whether it functions in neuronal survival, and whether growth and neuroprotective factors can induce its expression or activity. The report coherently describes in detail the background and the main objectives of the project, the work performed within it; and the results achieved.

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