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This paper critically assesses the scientific base that underpins the argument that oxidative damage is a significant causative factor in the development of human diseases and that antioxidants are capable of preventing or ameliorating these disease processes. The assessment has been carried out under a number of headings, and some recommendations for future research are made based on the present day knowledge base.

This is one of six thematic papers produced within the concerted action 'Functional Food Science in Europe' (FUFOSE), which is part of the European Commission's Fourth Framework Programme for research and technological development.

Additional information

Authors: DIPLOCK A T, International Antioxidant Research Centre, UMDS, Guy's Hospital, London (GB);RICE-EVANS C, International Antioxidant Research Centre, UMDS, Guy's Hospital, London (GB);CHARLEUX J-L, F. Hoffman-La Roche Ltd, Business Unit Carotenoids, Basel (CH);CROZIER-WILLI G, Nestec Ltd, Nestlé Research Centre, Lausanne (CH);KOK F J, Division of Human Nutrition and Epidemiology, Wageningen Agricultural University (NL);ROBERFROID M, UCL, École de Pharmacie, Brussels (BE);STAHL W, Heinrich-Heine-University Düsseldorf, Medizinische Enrichtungen, Institut für Physiologische Chemie, Düsseldorf (DE);VIÑA-RIBES J, Universidad de Valencia, Facultad de Medicina, Departamento de Fisiologia, Valencia (ES)
Bibliographic Reference: A paper published in 'Functional food science in Europe - volume 1', EUR 18591 EN, pp.S77-S112.
Availability: EUR-OP reference: CG-NO-18591-EN-S; price: 71 euros (set of 3 volumes). Available from EUR-OP sales agents. URL:
ISBN: ISBN: 92-828-4776-4 (3
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