Community Research and Development Information Service - CORDIS


How to make our hospitals a safer place, Strategies for control and prevention of antibiotic resistance in European hospitals



Antibiotics are rapidly losing their effectiveness and no longer warrant the description 'miracle drugs'. Due largely to the overuse and misuse of antibiotics, bacteria have become increasingly resistant to many of the compounds we rely on to treat serious infections in our hospitals.
Although many antibiotic-resistant bacteria exist, there are specific strains which frequently cause infection and cannot be treated with standard antibiotics, requiring alterations to routine therapeutic regimes. These bacteria are often particularly virulent, causing serious infections. Such bacteria are called 'alert organisms'. The atypical resistance phenotypes can only be detected by performing antibiotic susceptibility tests. Often, the alternative choice of antibiotic is less effective or toxic to the patient and clinical outcome is worse.

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