Community Research and Development Information Service - CORDIS


Control of assembly and charge transport properties of immobilized DNA (CIDNA) - Publishable Executive Summary

Project ID: 505669
Funded under: FP6-NMP


CiDNA was created with a view on opening new avenues in DNA-based biophysics, biochemistry and biotechnology with special focus on high temporal and spatial resolution towards the mesoscopic and single-molecule levels. The objectives were to be approached by cooperation between ten internationally recognized scientific partners and an industry partner active at the cutting edge of biotechnology.
Three major lines of fundamental and applied research were pursued with special emphasis on the dynamics of DNA-structures both in solution and immobilized on solid (metallic) surfaces in direct contact with an aqueous medium. The lines of cooperation were aiming at:
- New scientific pathways, where immobilized DNA structures in a functional state could be addressed at spatial levels ranging from solid/electrolyte monolayer down to single-molecule resolution.
- The dynamics of dye-labeled DNA conformations immobilized on surfaces controlled by fluorescence in a time range from picoseconds to minutes.
- The development of broad platforms for design, chemical synthesis, and comprehensive chemical and physical characterization of DNA-based molecular probes

Download application/pdf (972300)

Follow us on: RSS Facebook Twitter YouTube Managed by the EU Publications Office Top