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Bioengineered Nanomaterials for Research and Applications (BeNatural) - Publishable Executive Summary

Project ID: 33256
Funded under: FP6-NMP


BeNatural targets to use nature as model for new nanotechnology-based processes by applying fundamental knowledge from structure and assembly of biological nanofibers and nanotubes into new innovative ways of designing and assembling man-made nanodevices. The main objectives are: (i) to develop new self-assembling nanowires and nanotubes from building blocks inspired from natural folding and assembly motifs of proteins, (ii) to use these nanowires and nanotubes as templates for the growth of inorganic/nano/materials, (iii) to develop techniques to manipulate, assemble and position these materials in a controlled manner, in view of their integration in future generations of nanoscale devices, and (iv) to use the selfassembling nanostructures in biosensing and tissue engineering applications. More precisely, the activities of the participants are focused on the following main activities:
- identification of structurally recurring elements in natural fibrous proteins
- rational design and synthesis of self-assembling proteins and peptides
- structural characterization and assessment of the self-assembled blocks
- formation of biological/non-biological interface through modification of the selfassembling peptides and proteins
- manipulation, positioning and assembly of the inorganic nanowires and nanotubes
- use of nanotubes/nanowires and nanostructured networks in biosensing and tissue regeneration applications, respectively

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