Exploitable results Exploitable results – 6 meta-genomic libraries screened for different enzymatic activities (dioxygenases and oxygenases, lipases, cellulases, phosphatases and phytases) Result descriptionSix meta-genomic libraries were functionally screened and selected for different enzymatic activities (dioxygenases and oxygenases, lipases, cellulases, phosphatases and phytases). Result type* exploitable scientific result Link to resulthttps://www.microb3.eu/sites/default/files/deliverables/MB3_D7_5_PU.pdf References Exploitable results – Genome of the prokaryotic strain: Cycloclasticus zancles Result descriptionThe prokaryotic strain Cycloclasticus zancles, with exceptional functional capabilities for degradation of polyaromatic compounds and for sulfidogenic oxidation of acetate, has been isolated and its whole genome has been characterised. Result type* data Link to resulthttp://dx.doi.org/10.1371/journal.pone.0121178 ReferencesMathew, D. C., Ho, Y.-N., Gicana, R. G., et al. (2015) PLOS One Accession number: NC_021917 Exploitable results – M2B3 data reporting standard Result descriptionThe M2B3 Reporting Standard describes minimal mandatory and recommended contextual information for a marine microbial sample obtained in the epipelagic zone, includes meaningful information for researchers in the oceanographic, biodiversity and molecular disciplines, and can easily be adopted by any marine laboratory with minimum sampling resources. The M2B3 Service Standard defines a software interface through which these data can be discovered and explored in data repositories. Result type* guidelines/standards Link to resulthttp://dx.doi.org/10.1186/s40793-015-0001-5 References Exploitable results – Database of Minimum information on Biosynthetic Gene Clusters. Result descriptionA wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard. Result type* guidelines/standards Link to resulthttp://mibig.secondarymetabolites.org/ References Exploitable results – Ocean Sampling Day Repository for source code Result descriptionRepository for all Ocean Sampling Day (OSD) related source code with information on how-to access OSD data. Result type* data Link to resulthttps://github.com/MicroB3-IS/osd-analysis References Exploitable results – In silico screening method of Polyketide Synthases in Bacteria Result descriptionan in silico screening has been developed for the identification of interesting bacterial groups harbouring Polyketide Synthases (PKS) gene cluster matching to a specific consensus sequence. This model can be used as a compass for selection of the best candidates for drug discovery. Result type* other Link to result References Exploitable results – Consultancy for ABS legislation by user and provider states. Result descriptionConsultancy for ABS legislation by user and provider states. Knowledge on Access to (marine) microorganisms and Benefit-Sharing obtained can be used for providing consultancy concerning new ABS legislation, drafting ABS guidance for research funding organisations and for universities. Result type* other Link to result References Exploitable results – The Multivariate Analysis Applications for Microbial Ecology (MASAME) suite. Result descriptionThe Multivariate Analysis Applications for Microbial Ecology (MASAME) suite provides users with a means to perform multivariate analysis techniques through easy-to-use web applications. Result type* software/modelling tools Link to resulthttp://mb3is.megx.net/masame/ References Exploitable results – MegxMapWidget for integrating Genes Mapserver data into third party applications Result descriptionEasy to use widget for displaying and interacting with geographic maps from the Genes Mapserver. Result type* software/modelling tools Link to resulthttps://colab.mpi-bremen.de/wiki/display/microb3/MegxMapWidget References Exploitable results – Genomes of the prokaryotic strain: Halanaeroarchaeum sulfurireducens Result descriptionThe prokaryotic strain Halanaeroarchaeum sulfurireducens, with exceptional functional capabilities for degradation of polyaromatic compounds and for sulfidogenic oxidation of acetate, has been isolated and its whole genome has been characterised. Result type* exploitable scientific result Link to result ReferencesAccession number: CP008874 Exploitable results – 15 Phytases with high thermostability and high activity Result description15 phytases (myo-inositol hexakisphosphate phosphohydrolase) identified in metagenomic libraries. Relevant phytase clone selected, with most robust activity at hard operating conditions (high temperature and low pH). Clone shows high thermostability and high transformation useful in reducing phosphate excretion in animals when supplied in animal feedstuff. Result type* exploitable scientific result Link to resulthttps://www.microb3.eu/sites/default/files/deliverables/MB3_D7_5_PU.pdf References Exploitable results – MICRO B3 Model Agreement on Access to (marine) microorganisms and Benefit-Sharing Result descriptionMICRO B3 Model Agreement on Access to (marine) microorganisms and Benefit-Sharing; a free contribution to biological Resrach and Development (R&D) infrastructure. It can be used by other R&D projects, and its proprietary option can also be adopted by private companies. Result type* Report Link to resulthttps://www.microb3.eu/sites/default/files/pdf/MICRO_B3_ABS_model_agreement_17122013%20explanatory%20notes.pdf References Exploitable results – 3DM information systems for 7 Protein super-families Result description3DM information systems (a platform that collect, combine and integrate protein-related data) have been developed, for seven protein super-families. Result type* data Link to result References Exploitable results – Ocean Sampling Day Handbook Result descriptionBest practice guide and standard operating procedure for large scale sampling of microbial biodiversity. Result type* guidelines/standards Link to resulthttps://www.microb3.eu/sites/default/files/osd/OSD_Handbook_June_2015.pdf References Exploitable results – MiMeT DB: The Microbial Metagenomic Traits Database Result descriptionMiMeT DB contains a pre-calculated set of metagenomic traits described in Barberan et al. 2012 "Exploration of community traits as ecological markers in microbial metagenomes" for a large variety of public metagenomes. The traits included in the statistical analyses range from GC content to functional diversity, and deliver a valuable set of ecological markers in order to discriminate between habitats,geographic locations, or temporal samples. Furthermore, inter-trait relationships can be used as habitat descriptors or indicators of artifacts during sample processing. Result type* data Link to resulthttp://mb3is.megx.net/mg-traits References Exploitable results – Genes MapServer Result descriptionGene MapServer is a database for geo-referencing DNA sequences and relating them to environmental data. Result type* software/modelling tools Link to resulthttp://blast2.mpi-bremen.de/gms References Exploitable results – Ocean Sampling Day Registry Result descriptionOcean Sampling Day (OSD) Registry. The database and web sites for the registration of OSD participants and public access to sampling site data. Result type* data Link to resulthttp://mb3is.megx.net/osd-registry/; http://www.gigasciencejournal.com/content/4/1/27 References Exploitable results – Ocean Sampling Day Smartphone App Result descriptionOcean Sampling Day Smartphone App developed and tested. The OSD App provides the opportunity to enter environmental parameters plus an illustrative photo in an electronic “log sheet” which are sent to the OSD server. It is available for Android and iPhone. Result type* multimedia Link to resultwww.microb3.eu/myosd/osd-citizen-app References Exploitable results – A novel antibiotic, ‘Subtilomycin’, which shows bioactivity against a broad range of pathogens including multidrug resistant pathogens. Result descriptionA novel antibiotic, termed ‘Subtilomycin’ was purified which shows bioactivity against a broad range of pathogens including multidrug resistant pathogens. Result type* product Link to result ReferencesPhelan, R. W., Barret, M., Colter, P. D. et al. (2013) Marine Drugs, 11(6), 1878-1898. DOI: 10.3390/md11061878 Exploitable results – 79 phosphatases with robust activity at high temperature and low pH Result description79 phosphatases identified and clone selected for enzyme with best, most robust activity at high temperature and low Ph. They have been immobilized for further studies. Result type* exploitable scientific result Link to resulthttps://www.microb3.eu/sites/default/files/deliverables/MB3_D7_5_PU.pdf References Exploitable results – Eleven expression and four metagenomic libraries established and tested on their potential to express oxygenases, esterases, meta-cleavage and glycosyl-hydrolases and glycosyltrans-ferases now available. Result descriptioneleven expression and four metagenomic libraries established and tested on their potential to express oxygenases, esterases, meta-cleavage and glycosyl-hydrolases and glycosyltrans-ferases now available. Result type* exploitable scientific result Link to result ReferencesAlcaide, M., Tchigvintsev, A., Martinez-Martinez, M., et al. (2015) Applied and Environmental Microbiology, doi: 10.1128/AEM.03387-14; Yakimov, M. M., La Cono, V., Spada, G. L., et al. (2015) Environmental Microbiology, 17(2), 364-382, doi: 10.1111/1462-2920.12587; Alcadie, M., Stogios, P. J., Lafraya, A., et al. (2015) Environ. Microbiol., 17(2), 332-345, doi: 10.1111/1462-2920.12660; Yakimov, M. M., La Cono, V., Smedile, F., et al., (2014) Environmental Microbiology reports, 6(6), 709-722, doi: 10.1111/1758-2229.12192; Sorokin, D. Y., Kublanov, I. V., Gavrilov, S. N., et al. (2015) ISME Journa, doi: 10.1038/ismej.2015.79 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
