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Genetic sequencing of yeast chromosome XI

A high resolution physical map of yeast chromosome XI has been constructed from overlapping cosmid clones of 3 complete genomic libraries of yeast, constructed for this purpose. 100% of the entire chromosome XI sequence has been determined in final form. More than 330 putative protein coding genes have been discovered among which only 30% were known from classical genetic and molecular studies. Approximately 70% of the new genes have no clear homologue in databases, hence represent new type of genes, not discovered before in any other organism and not belonging to any of the known protein families.

Reported by

Institut Pasteur
Rue du Docteur Roux 25
75724 Paris
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