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mitochon Report Summary

Project ID: 338133
Funded under: FP7-IDEAS-ERC
Country: Spain

Mid-Term Report Summary - MITOCHON (Artificial Mitochondria for Health)

mitochon quests to build a biomimetic system able to produce the chemical energy in form of ATP inside the eukaryotic cell. To achieve this goal we have been working on three parallel research lines: the collection of the biological building blocks, the targeting and internalization of the biomimetic system into cultured cells and the release and tracing of the newly formed ATP inside the cell. Up to date, proteins, lipids and peptides have been successfully assembled into a functional artificial system. In addition, the vectorization of non-functional prototypes into target cells are routinely performed. Ongoing research is now optimizing the best strategy to supply and to accurately trace the molecular cargo within living cells. With the tools in hand, now the logical consequence and progression is to converge these research lines and to assemble the puzzle that will lead to the fabrication of artificial mitochondria.

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