Community Research and Development Information Service - CORDIS

H2020

GlOPID-R-Sec Report Summary

Project ID: 643434
Funded under: H2020-EU.3.1.

Periodic Reporting for period 2 - GlOPID-R-Sec (Global Research Collaboration for Infectious Disease Preparedness (GloPID-R) Secretariat)

Reporting period: 2016-07-01 to 2017-12-31

Summary of the context and overall objectives of the project

As shown by the latest Ebola outbreak, the world is not ready to mount a rapid and coordinated research response to a major epidemic. This outbreak and others have exposed the need for global preparedness in terms of surveillance, capacity building, research coordination or development of diagnostics, vaccines and therapeutics before an outbreak emerges. The capacity to implement research in the midst of a crisis is also critical to investigate the causes, dynamics and possible therapeutic responses to a given outbreak. Up to now, there was no platform for scientists and research funders to determine what needs to be done, identify the best solutions and channel the necessary funds efficiently.
The GloPID-R initiative (Global Research Collaboration for Infectious Disease Preparedness) is the only initiative of its kind to bring together scientific and funding organizations on a global scale. It aims to establish global preparedness for a coordinated and effective research response within 48 hours of any severe infectious disease outbreak.
The idea launched in 2013, took form in October of 2014 when a dozen major organizations agreed to join forces and sign the GloPID-R charter. These founding members are the European Commission, the Canadian Institute of Health and Research, Instituto Butantan, Instituto Fiocruz, Instituto de Salud Carlos III, the South African Medical Research Council, INSERM, the National Research Foundation of South Korea, Institut Pasteur Korea, the Thailand National Institute of Health, the Australian National Health and Medical Research Council and the U.S. Department of Health and Human Services.
The European Commission decided to fund a Secretariat to support this initiative and ensure its sustainability.
Two partners – Fondation Mérieux (FMX) and the University of Oxford (UOXF) – decided to join forces to install and implement this Secretariat. Both partners have been building and coordinating international networks that share the objectives of GloPID-R.
The role of the Secretariat is to provide support to this new GloPID-R network and to assist its members in building a sustainable GloPID-R platform, focusing on:
▪ mapping the obstacles and challenges to a rapid and coordinated response to an epidemic,
▪ supporting the establishment of a strategic agenda and of a response plan to address them,
▪ connecting research networks.

Work performed from the beginning of the project to the end of the period covered by the report and main results achieved so far

In support of the objectives of the GloPID-R network and under the authority of the Chairs of GloPID-R and its General Assembly, the Secretariat pursued a series of concrete objectives, covering the tasks outlined in the GloPID-R Charter and the HCO 4 – 2014 Work programme, comprising strategic, operational, dissemination and organisational support activities to be realised in this Coordination and Support Action.
More specifically, the Secretariat:
- provided constant organisational, administrative and secretarial support to the GloPID-R governance bodies: GloPID-R Board consisting of the GloPID-R Chair and Vice-Chairs, GloPID-R Assembly consisting of all GloPID-R members, the new Industry Stakeholder Group consisting of Industry representatives, GloPID-R Scientific Advisory Board (SAB);
- built on its survey of capacities and obstacles to an effective research response to set up a new Clinical Trial networks working group, aimed at better sharing knowledge and improving practices;
- updated the GloPID-R response plan to take into account the lessons learnt from the Zika outbreak;
- performed a mapping exercise of emergency funding mechanisms to increase the collective understanding of financial obstacles to action;
- supported capacity building by identifying data-sharing principles and implementation rules;
- supported strategic anticipation by helping the SAB identify and rank long-term research priorities;
- supported the GloPID-R response to specific outbreaks like the Yellow Fever outbreak in Angola or the Plague outbreak in Madagascar;
- created a specific scientific working group to address research challenges in relation to the Chikungunya virus;
- implemented the GloPID-R communication policy aimed at ensuring that GloPID-R stakeholders stay well-informed and aligned.
The GloPID-R network is well structured and gaining momentum. It is now composed of 27 members, showing its growing attractiveness.

Progress beyond the state of the art and expected potential impact (including the socio-economic impact and the wider societal implications of the project so far)

Apart from the concrete results and deliverables detailed in this report, the GloPID-R network and its Secretariat proved their usefulness in accelerating the global research response and funding decisions during the Zika outbreak in Brazil and the recent Plague outbreak in Madagascar. GloPID-R mobilized early, analysed quickly the main research gaps related to these two outbreaks, and was subsequently instrumental in funding a research response to better understand the Zika outbreak or in facilitating funding decisions to key research projects to understand the Plague outbreak (including the set-up of a survivors cohort by Institut Pasteur Madagascar).

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