Community Research and Development Information Service - CORDIS


NANOSCOPY Report Summary

Project ID: 336716
Funded under: FP7-IDEAS-ERC
Country: Norway

Mid-Term Report Summary - NANOSCOPY (High-speed chip-based nanoscopy to discover real-time sub-cellular dynamics)

The invention of super-resolution optical microscopy also referred as optical nanoscopy has provided us with a glimpse of future impacts on cell-biology and medical care. Far-field optical nanoscopy enable the discovery of sub-cellular nanoscale process in living cells, which in the past was only attainable by electron microscopy on fixed cells. The 2014 Nobel Prize in Chemistry was awarded to the developers of optical nanoscopy highlighting the high impact on nanoscopy on several disciplines. Although nanoscopy offers unprecedented opportunities, the vision to replace present day standard microscopes with optical nanoscopes is still far from reality due to technical and practical limitation of present day nanoscopy. The widespread adoption of nanoscopy is currently hindered by: a slow imaging speed, the complexity of the imaging setups, a significant cost, and the need for skilful and highly trained operators.

In this ERC project, we propose a paradigm shift to use a photonic integrated chip (PIC) to hold and illuminate the sample and a simple and affordable standard microscope to acquire super-resolved images. The vision of this ambitious project is to enable widespread availability of affordable waveguide chip based optical nanoscopes. During the first half phase of the ERC project we have shown the proof-of-principle of chip-based optical nanoscopy. We believe this will open a new of research and commercial activities towards cost-effective, simple to operate chip-based optical nanoscopy as mainstream optical imaging and diagnostic tool.

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