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H2020

GoMyTri Report Summary

Project ID: 645701
Funded under: H2020-EU.1.3.3.

Periodic Reporting for period 1 - GoMyTri (Golden Mycological Triangle – joining forces to exploit mycological biodiversity for novel anti-infectives and other beneficial metabolites)

Reporting period: 2015-01-01 to 2016-12-31

Summary of the context and overall objectives of the project

The cooperation is intended to explore the mycological and microbiological biodiversity of Europe and Southeast Asia, in particular with regard to the search for the badly needed new antibiotics and other biologically active substances.
It has various possible impacts on society, ranging from basic research on fungal evolution and ecology to drug research and development of new biological control agents to replace hazardous chemicals in agriculture.
The project will foster international collaboration networks, know-how exchange and interdisciplinary training of young scientists. The partners are three research infrastructure organisations in Germany, the Netherlands and Thailand that are recognised internationally as strongholds in mycological, biotechnological and microbiological research. In the medium term the project is aimed at attaining a sustrainable internationally visible strategic cooperation, including other departments of the institutions involved.
The project also includes the dissemination of data and results in Internet-based public domain databases and through interdisciplinary workshops, as well as on international conferences, to increase the awareness of the public and the stakeholders in industry, and to ultimately attract industrial partners from both the SME sector and the big Pharma/Agro industries

Work performed from the beginning of the project to the end of the period covered by the report and main results achieved so far

The first two years of the project were mainly dedicated to field work, and several hundreds of fungal cultures have been isolated from material mostly collected in Thailand. These fungal strains were characterised by morphological and molecular phylogenetic methods and several new taxa were discovered. The cultures are now undergoing screening for antimicrobial and namtgicidal metabolites and a number of bioactive metabolites have already been found, isolated and charactereised. The first publications have already been submitted.
During the course of the project eleven young researchers from Europe and Thailand were given the opportunity to work in the laboratory of the respective partner institutions and could learn new techniques and exchange methods and know-how with the staff of the host institute.

Progress beyond the state of the art and expected potential impact (including the socio-economic impact and the wider societal implications of the project so far)

The project is now still at a rather early stage, but the fact that the first joint publications of the project partners could already be submitted and many more are in the pipeline proves that the goal to set up a medium-to long term collaboration is feasible. Contacts of the European partners to other researchers in Thailand were already established and the first applications for grants for PhD candidates and postdocs between the partner institutions in the Netherlands, Germany and Thailand are already under way.
The ultimate goal of the project, i.e. to find candidate compounds for development of new antibiotics and other drugs. or fungal strains that are suitable for industrial partnering for bioligical control applications, however, can only be accomplished in the second phase of the project, as had already been envisaged in the working plan.
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