Service Communautaire d'Information sur la Recherche et le Développement - CORDIS

MAGNOBRAIN: biomagnetic methodologies for the non-invasive investigation of the human brain

Biomagnetism is a non-invasive technique well suited for monitoring the electrical activity of the brain. It infers information about the electric currents of the brain from measurements of the magnetic fields they induce. If biomagnetic information can be integrated with computerised tomography (CT) or magnetic resonance imaging (MRI) images or information from other functional evaluation and anatomical imaging techniques, then biomagnetism can serve as electromagnetic basis for 'functional imaging' of the brain.

The objective of MAGNOBRAIN is to integrate the disciplines of magneto-encephalography (MEG) and of evoked magnetic fields of the brain (EMF), with MRI and the electoencephalogram (EEG). MAGNOBRAIN-ANIMATOR has transformed the main MAGNOBRAIN output, ie the brain data base (BDB), into a marketable product by producing:
a survey of medical attitudes towards electromagnetic functional imaging in order to use it as a guide for the subsequent prototype design process;
necessary tools for matching any arbitrary MRI brain slice to the corresponding (and appropriate) BDB contents; these are envisaged as a set of tools that allow the local 'stretching' and 'shrinking' of MRI images so that they match the BDB model;
the development of interfaces for using EEG/ME along with MRI data for forward and inverse problem computations as well as for retrieval of information from the BDB.
The clinical evaluation of MAGNOBRAIN-ANIMATOR took place in 4 sites. In each site the MAGNOBRAIN-ANIMATOR has been tested for a period of 4 months on a common protocol. The MAGNOBRAIN-ANIMATOR product is marketed as a medical software product that will be highly portable and compatible with most forms of medical imaging.

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