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Frequency of satellite cells in young and old human muscle

The data on satellite cell frequency obtained in young and old human muscles can serve as a standard when comparing satellite cell frequency in pathological, disused or differently trained muscles.

Number of M-cadherin stained satellite cells in 1cm3 of human vastus lateralis muscles: 2.36 �8.97 x 105 (in the young), 1.85 �3.55 x 105 (in the old muscle) (non-significant difference).

Frequency of M-cadherin stained satellite cells in human vastus lateralis muscle:

1.85 ± 0.23 (SEM) per mm fibre length in the young, 1.19 ± 0.06 in the old muscle (p<0.05);
- Percentage of M-cadherin stained SC nuclei from total muscle nuclei 2.02 ± 0.33 in the young, 1.09± 0.12 in the old muscle (p<0.05);
- Per fibre number: 2.4 ±0.4 in the young, 1.6 ±0.1 in the old muscle (p<0.05).

These results might also be interesting for comparison among different species.

Reported by

University of Ljubljana, Medical Faculty
Korytkova 2
1000 Ljubljana
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