Service Communautaire d'Information sur la Recherche et le Développement - CORDIS

New and improved recombinant JSRV proteins

A number of different new plasmid constructs were made for the expression of recombinant JSRV proteins. Expression and purification of the proteins was optimised and the proteins were used as immunogens or as antigens for immunological assays. The proteins have further use for similar studies. In the right dose, adjuvant and immunisation route one or more of the proteins may be a component of a future vaccine against OPA. The same proteins could also be employed in assays to monitor vaccine efficacy in inducing immune responses.

Reported by

Moredun Research Institute
Pentlands Science Park, Penicuik
EH28 0PZ Edinburgh
United Kingdom