Community Research and Development Information Service - CORDIS

Structural studies have progressed knowledge on the organisation and subunit association of the stalk and membrane sector of the V-H+-ATPase complex

The identification of the binding sites for natural inhibitors of the enzyme complex and the structural characterisation of the proteins involved will both aid targeting and development of compounds for therapeutic intervention. The disposition of proteins in the membrane will further aid the availability of sites of interaction of synthetic compounds.

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Woodhouse Lane
United Kingdom
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