Servicio de Información Comunitario sobre Investigación y Desarrollo - CORDIS

Analysis of gene expression during DA neuron differentiation and after depolarization

We have used expanded DA cultures to identify genes important in DA differentiation. Oligonucleotide microarray analysis of 15866 genes showed that the number of genes up- and downregulated after 30’ and 120’ of exposure to high potassium were 62(up)/117(down) and 191(up)/92(down), respectively. Many of these genes are involved in important physiological processes.

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NATIONAL RESEARCH COUNCIL OF ITALY
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