Community Research and Development Information Service - CORDIS

Genomic tools for fine mapping bovine chromosome 11

We have mapped a large number of microsatellite and EST/gene markers onto the RH map for BTA11. There are now 138 markers on BTA11 with approximately 100 new markers, added since Williams in 2002, which at LOD 4 the linkage group spans the whole chromosome while at LOD 6 the linkage group is split.

This map allows for fine positioning of important markers. Generally linkage maps allow good positioning of markers over a large area within the chromosome, however, RH maps allow for reliable marker placement over shorter distances, particularly important for fine mapping of QTLs.

A total of 38 markers were included in the linkage map of BTA11 of 85.1 cM. Two alternative linkage maps were constructed, because there were discrepancies between map orders estimated from the project data, the MARC linkage map, project RH map and the bovine genome sequence (Btau 2.0; in the targeted region.

Reported by

MTT Agrifood Research Finland
31600 Jokioinen
Follow us on: RSS Facebook Twitter YouTube Managed by the EU Publications Office Top