Servicio de Información Comunitario sobre Investigación y Desarrollo - CORDIS

Novel signaling option for retinoid receptors

Study of retinoid and rexinoid receptors role in growth arrest differentiation and apoptosis in acute myeloid leukemias. Investigation on the role of the specific receptors in these biological functions and indications for combination treatments.

Molecular investigation on the role of RAR and RXR in the regulation of cell death alone or in combination with other signal transduction pathways. Novel paradigms for therapy.

Reported by

Dipartamento di Patologia Generale
Via L. Crecchio, 7, I-80138, Napoli, Italia
80138 Napoli
Italy
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