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3-dimensional structures of proteinases and proteinase/ inhibitor complexes

The crystal structures of the catalytic domain of the human matrix metalloproteinase 16 (MMP-16 alias MT3-MMP), of human full-length proMMP-1, of the complex between the catalytic domain of MMP-13 and the bovine tissue inhibitor of metallo proteinases 2 (TIMP-2), and of the truncated human MMP-9 catalytic domain in complex with various synthetic inhibitors have been determined.

Reported by

Max-Planck-Institute for Biochemistry
Proteinase Research Group, Am Klopferspitz 18
82152 Martinsried