Servizio Comunitario di Informazione in materia di Ricerca e Sviluppo - CORDIS

Standards for micro-array data MIAME and MAGE developed

MIAME describes the data and metadata that authors must provide to support conclusions drawn from a micro-array experiment in order to interpret it unambiguously and potentially to reproduce it. The MIAME document has two quite distinct aspects that serve two quite distinct purposes. The first is the vocabulary to describe the logical structure that is common to most micro-array experiments and the second is a simple checklist that can be consulted by those involved in publication of micro-array-based data. This structure provides a simple framework for describing a micro-array experiment, which might easily be adapted for micro-array data management software development.

The final version of the Minimum Information About a Micro-array Experiment (MIAME) was released in January 2005. The full description is available from During the run of TEMBLOR project, largely due to TEMBLOR dissemination activities MIAME has been accepted by most of the major scientific journals as a requirement for publishing microarray data.

MAGE consists of three parts - object model MAGE-OM, data exchange format MAGE-ML and toolkit MAGEstk. MAGE-ML has been automatically derived from Microarray Gene Expression Object Model (MAGE-OM), which is developed and described using the Unified Modelling Language (UML) a standard language for describing object models. Models described using UML have advantages over pure XML technologies (DTDs or XML Schemas) in many respects, especially for didactic purposes.

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