Service Communautaire d'Information sur la Recherche et le Développement - CORDIS

Final Activity Report Summary - SOLAR (Sulfolobus, a model archaeon for studying the orgin of eukaryotes and development of their information processing systems)

In the Research Proposal, two overall objectives were described for the SOLAR MCRTN network: (i) providing a unique opportunity for the training of young, talented, (mainly) European scientists in a multidisciplinary environment using cutting-edge post-genomic and biochemical technologies, and (ii) preforming research on the model archaeon Sulfolobus in order to gain insight in the processing of genetic information in eukaryotes. It is concluded that the two objectives have been accomplished, and that the SOLAR project has been very successful, both in terms of training of young scientific talents, and in performing state-of-the-art scientific research.

The former is illustrated by the ERs that already obtained their PhD degree, while the others are currently completing the writing of their PhD thesis. As to the high scientific level, this is obvious from the long list of publications, the intense collaborations (exchange of fellows and joint publications), and the list of scientific breakthroughs (published in top scientific journals):
Unravelling of anti-viral defence mechanism (P1, P2, P5, P8).
Discovery of archaeal viruses (P2, P6, P8).
DNA repair helicase structure (P5).
Archaeal CRISPR complex elucidated (P5).
Archaeal Isoprenoid pathway (P1).
DNA transfer by UV-inducible pili (P8 and P9).
Rotation of archaeal flagella, although they are type IV (P9).

The overall conclusion is that the SOLAR Marie Curie Research Training Network has been very successful. Attempts will certainly be made to extend the collaborative efforts of the SOLAR Consortium.

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