Community Research and Development Information Service - CORDIS

DNA biochips spotter

To perform experiments that study the complicated behaviour of genes, biotechnologists need to be equipped with modern techniques and devices. A new spotter for biochips which provides a large number of products that ensure high speed, precision and quality has been developed by ULP-Industrie.
DNA biochips spotter
Although it was believed that thousands of genes in living organisms function in a complicated way in order to create life, traditional methods in molecular biology could not conform to this idea. Researchers were working on a "one gene in one experiment" basis, which means that the throughput was limited and the "whole picture" of gene function was hard to obtain.

During recent years, a new technology, the DNA biochip, made it possible to monitor the whole genome on a single chip. This provided researchers with a better picture of the interactions among thousands of genes simultaneously. The process of fabricating biochips is mainly performed by hi-tech devices called spotters.

ULP-Industrie developed a spotter aiming to improve its operational capabilities when compared to the existing ones. An additional aim was to overcome common weak points of this procedure. This new spotter utilises robotics that ensures optimal performance in terms of speed and precision.

It has the ability to put a great number of products from a standard plate (384 or 1536 wells plate) on a silicate surface. Moreover the quantity of DNA products extracted is controlled and the quality of the spots and hooking of the DNA is ensured. The spotter also prevents problems such as projection and scattering of spots.

It is expected that the unique characteristics of the device will shortly provide a large number of products while ensuring that a high level of quality and precision is maintained.
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